DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gfzf and EEF1E1

DIOPT Version :9

Sequence 1:	NP_001014610.1	Gene:	gfzf / 40858	FlyBaseID:	FBgn0250732	Length:	1045	Species:	Drosophila melanogaster
Sequence 2:	NP_004271.1	Gene:	EEF1E1 / 9521	HGNCID:	3212	Length:	174	Species:	Homo sapiens

Alignment Length:	160	Identity:	34/160 - (21%)
Similarity:	59/160 - (36%)	Gaps:	44/160 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   850 RSEEYSKMNPQKEIPVLD-DDGFYLSESIAIMQYLCDKYAPDSTLYPQDVNVRAVINQRLCFNMG 913
            :..:||... :::||||. ::|..|:....|..:|. |.|....|.......:|::.|.|.:.:
Human    18 KGNKYSAQG-ERQIPVLQTNNGPSLTGLTTIAAHLV-KQANKEYLLGSTAEEKAIVQQWLEYRV- 79

  Fly   914 FYYAPISAHSMAPIFFDYKRTPMSLKKVQNALDVFETYLQRLGTKYAAGENITIADFALISATIC 978
               ..:..||             |...:...|....:||:  ...|..|.|.|:||..|.
Human    80 ---TQVDGHS-------------SKNDIHTLLKDLNSYLE--DKVYLTGYNFTLADILLY----- 121

  Fly   979 LEAINFDLHQFTL------------VNKWY 996
                 :.||:|.:            |::|:
Human   122 -----YGLHRFIVDLTVQEKEKYLNVSRWF 146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gfzf	NP_001014610.1	FLYWCH	18..87	CDD:282369
		FLYWCH	162..229	CDD:282369
		FLYWCH	365..432	CDD:282369
		FLYWCH	597..663	CDD:282369
		Thioredoxin_like	811..886	CDD:294274	10/36 (28%)
		GstA	812..1000	CDD:223698	34/160 (21%)
		GST_C_Delta_Epsilon	900..1017	CDD:198287	21/109 (19%)
EEF1E1	NP_004271.1	N-terminal	2..56		11/39 (28%)
		Linker	57..63		1/5 (20%)
		C-terminal	64..152		21/112 (19%)
		GST_C_AIMP3	65..165	CDD:198338	21/111 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900