DRSC/TRiP Functional Genomics Resources

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Protein Alignment gfzf and MARS1

DIOPT Version :9

Sequence 1:NP_001014610.1 Gene:gfzf / 40858 FlyBaseID:FBgn0250732 Length:1045 Species:Drosophila melanogaster
Sequence 2:NP_004981.2 Gene:MARS1 / 4141 HGNCID:6898 Length:900 Species:Homo sapiens


Alignment Length:243 Identity:52/243 - (21%)
Similarity:91/243 - (37%) Gaps:54/243 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   812 MKLYAVSDGPP------SLAVRMTLKALDIQYQLINVDFCAMEHRSEEYSKMNPQKEIPVLD-DD 869
            |:|: ||||.|      :.|.|...:| ::....:..:.|.:...:        :.::|||. |.
Human     1 MRLF-VSDGVPGCLPVLAAAGRARGRA-EVLISTVGPEDCVVPFLT--------RPKVPVLQLDS 55

  Fly   870 GFYLSESIAIMQY--LCDKYAPDSTLYPQDVNVRAVINQRL---------CFNMGFYYAPISAHS 923
            |.||..:.||.:|  |...:..|.           :.||.|         ..:...||..:..  
Human    56 GNYLFSTSAICRYFFLLSGWEQDD-----------LTNQWLEWEATELQPALSAALYYLVVQG-- 107

  Fly   924 MAPIFFDYKRTPMSLKKVQNALDVFETYLQRLGTKYAAGENITIADFALISATI-CLEAINFDLH 987
                    |:....|..|:.||...:..|.|....:.|||..::||..|..|.. .|:...:...
Human   108 --------KKGEDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPE 164

  Fly   988 QFTLVNKWYETFKVEYP--QLWE--IANSGMQEISAFEQNPPDMSHME 1031
            :.:.::.|::|...:.|  :..|  :...|:..:..:.|..|..|..|
Human   165 ELSALHSWFQTLSTQEPCQRAAETVLKQQGVLALRPYLQKQPQPSPAE 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gfzfNP_001014610.1 FLYWCH 18..87 CDD:282369
FLYWCH 162..229 CDD:282369
FLYWCH 365..432 CDD:282369
FLYWCH 597..663 CDD:282369
Thioredoxin_like 811..886 CDD:294274 22/82 (27%)
GstA 812..1000 CDD:223698 45/206 (22%)
GST_C_Delta_Epsilon 900..1017 CDD:198287 25/130 (19%)
MARS1NP_004981.2 Thioredoxin_like <27..68 CDD:294274 10/48 (21%)
GstA <47..189 CDD:223698 36/162 (22%)
GST_C_MetRS_N 77..179 CDD:198340 23/122 (19%)
PRK12268 264..819 CDD:237029
MetRS_core 265..633 CDD:173907
'HIGH' region 273..283
'KMSKS' region 593..597
Anticodon_Ia_Met 642..771 CDD:153411
MetRS_RNA 845..889 CDD:238475
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0625
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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