DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gfzf and GstE3

DIOPT Version :9

Sequence 1:	NP_001014610.1	Gene:	gfzf / 40858	FlyBaseID:	FBgn0250732	Length:	1045	Species:	Drosophila melanogaster
Sequence 2:	NP_611325.2	Gene:	GstE3 / 37108	FlyBaseID:	FBgn0063497	Length:	220	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	72/217 - (33%)
Similarity:	117/217 - (53%)	Gaps:	17/217 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   812 MKLYAVSDGPPSLAVRMTLKA--LDIQYQLINVDFCAMEHRSEEYSKMNPQKEIPVLDDDGFYLS 874
            :.||.:...||..:|.:||:|  ||..|:::|:  ...||...|:.|:||...:|.|||:||||:
  Fly     4 LTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNL--MEKEHLKPEFLKINPLHTVPALDDNGFYLA 66

  Fly   875 ESIAIMQYLCDKYAPDSTLYPQDVNVRAVINQRLCFNMGFYYAPISAHSMAPIFFDYK-RTPM-- 936
            :|.||..||..||..:.:|||:|:..||:::|||.::.....:...|.:. |:|::.| ..|.
  Fly    67 DSHAINSYLVSKYGRNDSLYPKDLKKRAIVDQRLHYDSSVVTSTGRAITF-PLFWENKTEIPQAR 130

  Fly   937 --SLKKVQNALDVFETYLQRLGTKYAAGENITIADFALISA-TICLEAINFDLHQFTLVNKWYET 998
              :|:.|..:|::|   |:  ...|.||:|:|||||.:|:. |.....:..|..::..:..|.:.
  Fly   131 IDALEGVYKSLNLF---LE--NGNYLAGDNLTIADFHVIAGLTGFFVFLPVDATKYPELAAWIKR 190

  Fly   999 FKVEYPQLWEIANSGMQEISAF 1020
            .| |.|...|...|...:|..|
  Fly   191 IK-ELPYYEEANGSRAAQIIEF 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gfzf	NP_001014610.1	FLYWCH	18..87	CDD:282369
		FLYWCH	162..229	CDD:282369
		FLYWCH	365..432	CDD:282369
		FLYWCH	597..663	CDD:282369
		Thioredoxin_like	811..886	CDD:294274	31/75 (41%)
		GstA	812..1000	CDD:223698	65/195 (33%)
		GST_C_Delta_Epsilon	900..1017	CDD:198287	33/122 (27%)
GstE3	NP_611325.2	GstA	4..195	CDD:223698	67/199 (34%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	31/74 (42%)
		GST_C_Delta_Epsilon	91..208	CDD:198287	33/123 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I643
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	8	7.920