DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gfzf and gst1

DIOPT Version :9

Sequence 1:	NP_001014610.1	Gene:	gfzf / 40858	FlyBaseID:	FBgn0250732	Length:	1045	Species:	Drosophila melanogaster
Sequence 2:	NP_588298.1	Gene:	gst1 / 2538694	PomBaseID:	SPCC191.09c	Length:	229	Species:	Schizosaccharomyces pombe

Alignment Length:	205	Identity:	57/205 - (27%)
Similarity:	91/205 - (44%)	Gaps:	17/205 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   814 LYAVSDGPPSLAVRMTLKALDIQYQLINVDFCAMEHRSEEYSKMNPQKEIPVLDD---DGFYLSE 875
            |::.:.||....|...||.||:.|:...|:|...|.:|.|:..:||...:|.|.|   :.:.:.|
pombe     6 LWSHAHGPNPWKVVQALKELDLTYETRYVNFSKNEQKSPEHLALNPNGRVPTLIDHHNNDYTIWE 70

  Fly   876 SIAIMQYLCDKYAPDSTL-YPQDVNVRAVINQRLCF---NMGFYYAP---ISAHSMAPIFFDYKR 933
            |.||:.||.|||..:..: .|:|......:.|.|.|   ..|..:..   .|.:....:.....|
pombe    71 SDAILIYLADKYDTERKISLPRDHPEYYKVIQYLFFQASGQGIIWGQAGWFSVYHQELVISAITR 135

  Fly   934 TPMSLKKVQNALDVFETYLQRLGTKYAAGENITIADFALISATICLEAINFDLHQFTLVNKWYE- 997
            ....:|:|   |.|.|..|:  ...|......||||.:.||....||.| |...:|::..:..:
pombe   136 YRNEIKRV---LGVLEDILK--DRDYLVANRFTIADLSFISWNNFLEII-FAEGKFSIEEEVPQL 194

  Fly   998 TFKVEYPQLW 1007
            .|:.|:|:.:
pombe   195 DFEKEFPRTY 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gfzf	NP_001014610.1	FLYWCH	18..87	CDD:282369
		FLYWCH	162..229	CDD:282369
		FLYWCH	365..432	CDD:282369
		FLYWCH	597..663	CDD:282369
		Thioredoxin_like	811..886	CDD:294274	25/74 (34%)
		GstA	812..1000	CDD:223698	54/196 (28%)
		GST_C_Delta_Epsilon	900..1017	CDD:198287	27/115 (23%)
gst1	NP_588298.1	GST_N_Ure2p_like	3..84	CDD:239346	28/77 (36%)
		GstA	5..218	CDD:223698	57/205 (28%)
		GST_C_Ure2p	96..219	CDD:198326	27/115 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	1	0.960	-	-
	5	4.770