Protein Alignment gfzf and Vars

DIOPT Version :9

• Sequence 1: NP_001014610.1
• Gene: gfzf / 40858
• FlyBaseID: FBgn0250732
• Length: 1045
• Species: Drosophila melanogaster
• Sequence 2: NP_035820.3
• Gene: Vars / 22321
• MGIID: 90675
• Length: 1263
• Species: Mus musculus
• Alignment Length: 614
• Identity: 119/614 - (19%)
• Similarity: 193/614 - (31%)
• Gaps: 233/614 - (37%)

  Fly   188 GDIFRW--TCVRKRDIECTARICTEATLAGAHRLHAVDTDAHIHPHYSAAKLMHMFSKHQIVLVE 250
            |::.||  ||||:.  |..|.:...|..:||..:........|.|..:.|:|.....|.:
Mouse   185 GNVTRWFNTCVRQP--EFRAVLGEVALYSGARSVTQQPGSEVIAPQKTPAQLKKEAKKRE----- 242

  Fly   251 DENTSDVLAECPNLEYF-DPENTFDTAQRGDDLESIIIEECED----NYDIYMRTDGSQGGGIQG 310
                        .||.| ..:.|......|:.......:|..|    .||
Mouse   243 ------------KLEKFQQKQKTQQQPPHGEKKPKPEKKEKRDPGVITYD--------------- 280

  Fly   311 SEELESQEGDDESSLVDPKMHHSSKWPAAFD---VIANYLP---------PPSHNPLTETDLTKF 363
               |.:..|:        |...|...|.::.   |.|.:.|         |....|....
Mouse   281 ---LPTPPGE--------KKDVSGAMPDSYSPQYVEAAWYPWWERQGFFKPEYGRPSVSA----- 329

  Fly   364 TFLPSAKGRKVLCL-------SQHLFHFDSQSRSNGHMFFTCINRRDKANTCHVRITLDPVENGP 421
               |:.:|..::|:       |.||          ||.....|  :|.....|
Mouse   330 ---PNPRGVFMMCIPPPNVTGSLHL----------GHALTNAI--QDSLTRWH------------ 367

  Fly   422 VVLRINGEHT-HNP--DIKEIARRLKQQAKLDQD---NVHKLQKIEHSEEI-SFESDEGSASQGG 479
               |:.||.| .||  |...||.::..:.||.::   |.|:|.:....||: .:::::|
Mouse   368 ---RMRGETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFLEEVWKWKAEKG------ 423

  Fly   480 DTFEAENSVDESYGHIDTRNVVMKKV-ISID---GAIKMEPESKANMIVQYLKDGANNISAKIEI 540
                     |..|..       :||: .|:|   ....|:|:..|.:...:::
Mouse   424 ---------DRIYHQ-------LKKLGSSLDWDRACFTMDPKLSATVTEAFVR------------ 460

  Fly   541 LPDALDELDPHSHTAYSSTPLPKVRQPQITNIRRRRDVAEPAKGAQPDMDLSKICTLRSA----- 600
                |.|    ....|.||.|                             ::..|||.||
Mouse   461 ----LHE----EGVIYRSTRL-----------------------------VNWSCTLNSAISDIE 488

  Fly   601 ------KGHELLCVDGYIYHAKNRGVISRNYWVCIKSRDPD---INCKSRISTATQKDGSIRVLR 656
                  .|..||.|.||....:...::|..|.|  :..|.|   :...:||.|..   |.:.|.
Mouse   489 VDKKELTGRTLLPVPGYKEKVEFGVLVSFAYKV--QGSDSDEEVVVATTRIETML---GDVAVA- 547

  Fly   657 VYNSHSHPFSEDDIKRRLYNEINKKNNKNLKFRPLHFIGKSL-----DQIQQEYGDLAIERLNVS 716
                 .||      |...|..:..|    ....|  |:.:||     |.:..|:|..|: ::..:
Mouse   548 -----VHP------KDPRYQHLKGK----CVVHP--FLSRSLPIVFDDFVDMEFGTGAV-KITPA 594

  Fly   717 NISSDIVVHKKPRVSGSN--NSRSASLSV 743
            :..:|..|.::.|:...:  :|:.|.::|
Mouse   595 HDQNDYEVGQRHRLEAISIMDSKGALINV 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gfzf	NP_001014610.1	FLYWCH	18..87	CDD:282369
		FLYWCH	162..229	CDD:282369	12/42 (29%)
		FLYWCH	365..432	CDD:282369	15/74 (20%)
		FLYWCH	597..663	CDD:282369	19/79 (24%)
		Thioredoxin_like	811..886	CDD:294274
		GstA	812..1000	CDD:223698
		GST_C_Delta_Epsilon	900..1017	CDD:198287
Vars	NP_035820.3	GST_C_family	92..213	CDD:383119	10/29 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..294		18/118 (15%)
		PTZ00419	281..1263	CDD:240411	93/481 (19%)
		'HIGH' region	343..353		3/19 (16%)
		'KMSKS' region	861..865

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900