DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gfzf and Y53G8B.1

DIOPT Version :9

Sequence 1:	NP_001014610.1	Gene:	gfzf / 40858	FlyBaseID:	FBgn0250732	Length:	1045	Species:	Drosophila melanogaster
Sequence 2:	NP_497662.1	Gene:	Y53G8B.1 / 190243	WormBaseID:	WBGene00021817	Length:	213	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	59/231 - (25%)
Similarity:	101/231 - (43%)	Gaps:	46/231 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   814 LYAVSDGPPSLAVR--MTLKALDIQYQLINVDFCAMEHRSEEYSKMNPQKEIPVLDDDGFYLSES 876
            ||:......|..||  :.||.:|.:||.:|:   ..:.:.:|:...||.:::|:|..:|..|:||
Worm     7 LYSSWSSGCSSRVRTALALKKIDYEYQPVNL---LNKQKEQEFHGNNPAEKVPILKINGLTLTES 68

  Fly   877 IAIMQYLCDKYAPDSTLYPQDVNVRAVINQRLCFNMGFYYAPISAHSMAPIFFDYKRTPMSLKK- 940
            :||::|| |:..||..|.|::..::|.. :.:.|::.....|:   ...||:.      |..:|
Worm    69 MAIIEYL-DEIYPDPPLLPKEPELKARA-RAIAFHIASNIQPL---QNKPIYL------MLNEKE 122

  Fly   941 -----------VQNALDVFETYLQRLGTKYAAGENITIADFALISATICLEAINFDLHQFTLVNK 994
                       :.......|..||.....:..|..|:|||       |||.:|     .:..:.|
Worm   123 PGYGDFWCQHFISKGFKALEELLQMHSGDFCVGNQISIAD-------ICLPSI-----VYNAIEK 175

  Fly   995 WYETFKVEYPQLWEIANSGMQEISAFE----QNPPD 1026
             |......||.:..|:|. :.|:..|:    .|.||
Worm   176 -YHVDMTPYPIITRISNK-LAELPEFQVAHPNNQPD 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gfzf	NP_001014610.1	FLYWCH	18..87	CDD:282369
		FLYWCH	162..229	CDD:282369
		FLYWCH	365..432	CDD:282369
		FLYWCH	597..663	CDD:282369
		Thioredoxin_like	811..886	CDD:294274	24/73 (33%)
		GstA	812..1000	CDD:223698	50/199 (25%)
		GST_C_Delta_Epsilon	900..1017	CDD:198287	25/128 (20%)
Y53G8B.1	NP_497662.1	Thioredoxin_like	5..76	CDD:294274	24/72 (33%)
		maiA	18..211	CDD:273527	56/220 (25%)
		GST_C_Zeta	89..207	CDD:198300	27/141 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810