DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gfzf and gst-42

DIOPT Version :9

Sequence 1:	NP_001014610.1	Gene:	gfzf / 40858	FlyBaseID:	FBgn0250732	Length:	1045	Species:	Drosophila melanogaster
Sequence 2:	NP_509962.1	Gene:	gst-42 / 183911	WormBaseID:	WBGene00001790	Length:	214	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	59/229 - (25%)
Similarity:	98/229 - (42%)	Gaps:	43/229 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   814 LYAVSDGPPSLAVRMTLKALDIQYQLINVDFCAMEHRSEEYSKMNPQKEIPVLDDDGFYLSESIA 878
            ||:......|..||:.|...::.|:...||..:.|.:| :..::||..::|....||..::||:|
Worm     8 LYSYWRSSCSWRVRIALALKNVDYEYKTVDLLSEEAKS-KLKEINPAAKVPTFVVDGQVITESLA 71

  Fly   879 IMQYLCDKYAPDSTLYPQD----VNVRAVINQRLCFNMGFYYAPISAHSMAPIFFDYKRTPMSLK 939
            |::|| ::..||..|.|:|    .:.||:             :.:.|..:.|: .:.|...:..|
Worm    72 IIEYL-EETHPDVPLLPKDPIKRAHARAI-------------SLLVASGIQPL-HNLKVLQLLNK 121

  Fly   940 K------------VQNALDVFETYLQRLGTKYAAGENITIADFALISATICLEAINFDLHQFTLV 992
            |            |...|...|..|::...|||.|:::||||.::..........|.||..:..|
Worm   122 KEAGFGGQFAKQFVVEGLTALEILLKQHSGKYAVGDDVTIADLSIPPLIYSANRFNLDLSPYPTV 186

  Fly   993 NKWYETFKVEYPQLWEIANSGMQEISAFEQNPPD 1026
            |:..||. .:.|..          |:|...|.||
Worm   187 NRINETL-ADIPAF----------IAAHPDNQPD 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gfzf	NP_001014610.1	FLYWCH	18..87	CDD:282369
		FLYWCH	162..229	CDD:282369
		FLYWCH	365..432	CDD:282369
		FLYWCH	597..663	CDD:282369
		Thioredoxin_like	811..886	CDD:294274	22/71 (31%)
		GstA	812..1000	CDD:223698	53/201 (26%)
		GST_C_Delta_Epsilon	900..1017	CDD:198287	27/128 (21%)
gst-42	NP_509962.1	GST_N_Zeta	6..77	CDD:239340	22/70 (31%)
		maiA	7..211	CDD:273527	59/229 (26%)
		GST_C_Zeta	90..207	CDD:198300	29/141 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810