DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10098 and Scrn3

DIOPT Version :9

Sequence 1:	NP_649694.1	Gene:	CG10098 / 40851	FlyBaseID:	FBgn0037472	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	XP_006234420.1	Gene:	Scrn3 / 311731	RGDID:	1305064	Length:	418	Species:	Rattus norvegicus

Alignment Length:	421	Identity:	112/421 - (26%)
Similarity:	174/421 - (41%)	Gaps:	86/421 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DCFVVLPENCAEGTLIIGRNAE---DEKNVNVASEVCFYDAT--EVLEGK-----TDGGASAETG 59
            |.||.||.......:|.|:|::   ||     ..||.::.|.  ..||.:     .:.....||
  Rat     7 DTFVALPPATVGNRVIFGKNSDRLFDE-----VQEVIYFPAAVHSDLEKRLKCTYIEVDQVPET- 65

  Fly    60 GDMLRVILQKPQPGLWGGDFGANERGVALGLTWAAGENEAKDSDSLLGTDIVRLTLAVAKDVDDA 124
               ..|:|.:| ..|||.:.||||.||.:|.....|..:....::|||.|:|||.|..|...:.|
  Rat    66 ---YAVVLSRP-AWLWGAEMGANEHGVCIGNEAIWGREDISKEEALLGMDLVRLGLERADTAEKA 126

  Fly   125 VDRIGALVASHGHDNSKL---------NFIACDAAAAWLVSCSGKVWAAEKLEASFLRLPSGGLA 180
            ::.|..|:..:|...:..         :|:..|...||::..|||.|||||::.  :|..|...:
  Rat   127 LNVIVDLLGKYGQGGNCAEGEEFSYYNSFLIADRNEAWILETSGKFWAAEKVQG--VRNISNQFS 189

  Fly   181 VTTVVNK----------------SSEGLDDAASFAAAHDAEAQAPAVDWC-GPKPAG--DGTYTQ 226
            :||.:::                ..|..|.||:::....|........:| |.|...  .|..|.
  Rat   190 ITTKIDREHPDMRNYAKQRGWWDGKEEFDFAAAYSYTDTATMMTSPSRYCQGHKLLNKHKGNITY 254

  Fly   227 HDMFETLR---SASNASSSRAATVSVLSV----KGISC-HWFTGTPNAAESVFKPFVFAPNPRIS 283
            ..|.|.||   |..|.......|.|::|:    ..:.| |..||||:...||||||:|.|:  :|
  Rat   255 ETMVEILRDRPSGINMKGEFLTTASMVSILPQDPSLPCIHLLTGTPHPERSVFKPFIFVPH--VS 317

  Fly   284 PLTQVQA-----EADLT-----------LLHKLHSQ----------RKPAALEHLRSLELSCVDE 322
            ||...::     |..:.           ||::.|.|          :....|:::|.||....:|
  Rat   318 PLLDTKSPTFELERPVAKKPYVKPDRRHLLYQNHQQALEMISNHKEKGKTILDNVRKLEKEVFEE 382

  Fly   323 LNNYFSLQDHASDELDELLKDCVEAEVKFYR 353
            :.:....:....|:...|....|..|:|.|:
  Rat   383 IESILQNRHLDMDKTVNLFPQYVRDEIKIYQ 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10098	NP_649694.1	Ntn_hydrolase	73..>169	CDD:294319	36/104 (35%)
Scrn3	XP_006234420.1	Ntn_hydrolase	5..>224	CDD:294319	64/228 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340491
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11601
Inparanoid	1	1.050	106	1.000	Inparanoid score	I4835
OMA	1	1.010	-	-		QHG47750
OrthoDB	1	1.010	-	-		D322959at2759
OrthoFinder	1	1.000	-	-		FOG0002049
OrthoInspector	1	1.000	-	-		otm45684
orthoMCL	1	0.900	-	-		OOG6_105994
Panther	1	1.100	-	-	O	PTHR12994
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X7557
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770