DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alh and SDG14

DIOPT Version :9

Sequence 1:	NP_001262332.1	Gene:	Alh / 40850	FlyBaseID:	FBgn0261238	Length:	1717	Species:	Drosophila melanogaster
Sequence 2:	NP_191733.3	Gene:	SDG14 / 825347	AraportID:	AT3G61740	Length:	1018	Species:	Arabidopsis thaliana

Alignment Length:	364	Identity:	102/364 - (28%)
Similarity:	154/364 - (42%)	Gaps:	77/364 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TIHSTSLNK-KLVKIKKFKLDDM--KEMVGGCCVCSDERGWPENPLVYCDGQNCTVAVHQACYGI 94
            |:.:..|:| |::.:.:.|.:.:  |.....|.||.....|.||.::.|:  .|.|||||.|||:
plant   518 TLETQMLDKQKMLSLLEEKYEPVRAKWTTERCAVCRWVEDWEENKMIICN--RCQVAVHQECYGV 580

  Fly    95 -VTVPTGPWYCRKCESQ--ERTSRVRCELCPSRDGALKKTDNSG-WAHVVCALYIPEVRFGNVTT 155
             .:.....|.||.||:.  ||.    |.|||.:.||||.:|..| |.||.||.:.|||.|.|...
plant   581 SKSQDLTSWVCRACETPDIERD----CCLCPVKGGALKPSDVEGLWVHVTCAWFRPEVGFLNHEN 641

  Fly   156 MEPII-LSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGN 219
            |||.: |..||...:.|.|.||::       ..|:|:.|.|  |...||..||...|...|
plant   642 MEPAVGLFKIPANSFLKVCTICKQ-------THGSCVHCCK--CATHFHAMCASRAGYNME---- 693

  Fly   220 YLDNVKYCGYCQHHYSKLKKGGNVKTIPPYKPIQHDTSSDSCSSPEK-EIDSTMNSATTSATIIK 283
                 .:|         |:|.|          :|....|..||...| :.||          ::.
plant   694 -----LHC---------LEKNG----------VQRTRKSVYCSFHRKPDPDS----------VVV 724

  Fly   284 ITSSSGSAGGSSNVLNASSSAGISAGSSSGSGVSSSAKQRKSNASSKSSSSSS---SSSSSSTGG 345
            :.:.|| ..||.|:|..      ..|.:.||.:..:.|.:.....:::.:..|   .|.|::...
plant   725 VHTPSG-VFGSRNLLQN------QYGRAKGSRLVLTKKMKLPGFQTQTQAEQSRVFDSLSAARCR 782

  Fly   346 APNPSSSSVHSGSASNMTGGGSVLPGSSNIGNISNSLNN 384
            ..:.|::.:...:.|:...|    |...::..|.| ||:
plant   783 IYSRSNTKIDLEAISHRLKG----PSHHSLSAIEN-LNS 816

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	19/47 (40%)
Alh	NP_001262332.1	ePHD_AF10_like	118..233	CDD:277142	42/116 (36%)
SDG14	NP_191733.3	WHSC1_related	187..290	CDD:99899
		PHD_TCF19_like	365..415	CDD:276992
		PHD_ATX3_4_5_like	548..594	CDD:276970	19/47 (40%)
		ePHD_ATX3_4_5_like	603..714	CDD:277133	49/147 (33%)
		SET	875..992	CDD:214614
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910