DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alh and brpf3

DIOPT Version :9

Sequence 1:	NP_001262332.1	Gene:	Alh / 40850	FlyBaseID:	FBgn0261238	Length:	1717	Species:	Drosophila melanogaster
Sequence 2:	XP_031751953.1	Gene:	brpf3 / 779492	XenbaseID:	XB-GENE-6092087	Length:	992	Species:	Xenopus tropicalis

Alignment Length:	280	Identity:	95/280 - (33%)
Similarity:	135/280 - (48%)	Gaps:	61/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IPSSF-----------NAKLELDSSKDDTIHSTSLNKK-------LVKIKKFKL--------DDM 54
            :|.||           :.::|.|..:.|......:|:|       ||....|:|        ..|
Frog   146 LPDSFYCYIERSTKEMDQEVEYDLDEVDLAWLEMINEKRKNDGLSLVSADVFELLLDRLEKESYM 210

  Fly    55 KEMVGG-----------CCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCE 108
            :....|           ||||.|:.....|.:::||  .|.:||||.|||:..:|.|.|.||.|
Frog   211 QSRRSGAPQSAIDEDAFCCVCLDDECHNSNAILFCD--ICNLAVHQECYGVPYIPEGQWLCRCC- 272

  Fly   109 SQERTSRVRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPII-LSLIPQERYSKT 172
            .|..:..|.|.|||::.||.|:|.:..|||||||::||||.|.|...:||:. ::.||..|:..|
Frog   273 LQSPSKPVSCVLCPNQGGAFKQTSDGRWAHVVCAIWIPEVCFANTVFLEPVEGVNNIPSARWKLT 337

  Fly   173 CYICQEIGKPNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCE-----EAG--NYLDNVKYCGYC 230
            ||:|::.|:      ||.:||:|.||...|||||||..||..:     |.|  .....|:...:|
Frog   338 CYLCKQKGR------GAAIQCHKVNCYTAFHVTCAQRAGLFMKVEPVRETGLNGTTFTVRKTAFC 396

  Fly   231 QHH-----YSK--LKKGGNV 243
            :.|     :.|  |:.||.|
Frog   397 ELHCPPGTHKKGILRCGGKV 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	22/57 (39%)
Alh	NP_001262332.1	ePHD_AF10_like	118..233	CDD:277142	51/122 (42%)
brpf3	XP_031751953.1	EPL1	58..207	CDD:402235	12/60 (20%)
		COG5141	165..610	CDD:227470	92/261 (35%)
		PHD_SF	282..399	CDD:419867	51/122 (42%)
		Bromodomain	585..682	CDD:413371
		BR140_related	860..976	CDD:99900
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566217at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1726
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.040