DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alh and kdm4c

DIOPT Version :9

Sequence 1:	NP_001262332.1	Gene:	Alh / 40850	FlyBaseID:	FBgn0261238	Length:	1717	Species:	Drosophila melanogaster
Sequence 2:	NP_001077320.1	Gene:	kdm4c / 570194	ZFINID:	ZDB-GENE-070209-38	Length:	1482	Species:	Danio rerio

Alignment Length:	253	Identity:	79/253 - (31%)
Similarity:	114/253 - (45%)	Gaps:	50/253 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 KEMVGGCCVCSDERGWPEN---------PLVYCDGQNCTVAVHQACYGIVTVPTGP-WYCRKCES 109
            :.::...|....|...|.|         |||.|  .:|.|.||.:|||:.....|| |.|.:|.|
Zfish  1116 RPLIPEICFAYQEGPCPLNTLLEEDGSSPLVVC--SSCCVQVHASCYGVSAQDVGPVWTCDRCVS 1178

  Fly   110 QERTSRVRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCY 174
            ::..:  .|.||..|.||||:|.:..|.||:||:.:|||:|.:|....||.:|.:|.:||...|.
Zfish  1179 EDLAA--GCCLCNLRGGALKRTSDDRWVHVMCAVGLPEVKFIDVVKRAPIDISAVPVQRYKLKCI 1241

  Fly   175 ICQEIGKPNRAN--VGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGY--CQHHYS 235
            .|:     ||..  .|||:||:...|...||||||.:.|:..|.     |:..|..:  |..|.|
Zfish  1242 YCR-----NRIKRLSGACIQCSCGRCPTSFHVTCAHAAGVPMEP-----DDWPYVVFITCHRHQS 1296

  Fly   236 KLKKGGNVKTIPPYKPIQHDTSSDSCSSPEKEIDSTM-----NSATTSATIIKITSSS 288
            : .....||.                |..|.|:..|:     |....|:.|.::|:.:
Zfish  1297 R-SSSAKVKV----------------SKSELEVGQTVISKHKNLRYYSSRITQVTAQT 1337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	19/56 (34%)
Alh	NP_001262332.1	ePHD_AF10_like	118..233	CDD:277142	46/118 (39%)
kdm4c	NP_001077320.1	JmjN	16..57	CDD:128818
		JmjC	177..293	CDD:202224
		PHD_SF	1079..1176	CDD:304600	19/61 (31%)
		ePHD_JMJD2C	1185..1294	CDD:277185	46/118 (39%)
		TUDOR	1308..1364	CDD:197660	7/30 (23%)
		TUDOR	1366..1421	CDD:197660
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910