DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alh and Phf14

DIOPT Version :9

Sequence 1:	NP_001262332.1	Gene:	Alh / 40850	FlyBaseID:	FBgn0261238	Length:	1717	Species:	Drosophila melanogaster
Sequence 2:	XP_006236166.1	Gene:	Phf14 / 500030	RGDID:	1563764	Length:	950	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	100/369 - (27%)
Similarity:	149/369 - (40%)	Gaps:	73/369 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RNNNKQVTSSNKIPSS--FNAKLELDSSK---DDTIHSTSLNKKLVKIKKFKLDDMKEMVGGCCV 63
            :....:|.|.|.....  .|..|.|..||   |..|...|.|....|:....:         |||
  Rat   261 KKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQNWSSQKMDHILI---------CCV 316

  Fly    64 CSDERGWPENPLVYCDGQNCTVAVHQACYGI-----------VTVPTGPWYCRKCESQERTSRVR 117
            |..:.....:.::.||  ||.:.||:.|||:           ....|.||:|..|:.....|
  Rat   317 CLGDNSEDADEIIQCD--NCGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKCGVSPS--- 376

  Fly   118 CELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERY-SKTCYICQEIGK 181
            |||||::||..|:||...|.|:|||||:|.|.||::..:.|:.|:.:...:| :|.|..|::
  Rat   377 CELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCED--- 438

  Fly   182 PNRANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKTI 246
            |..|..|.|:.|:...|:..|||||||..|||.|.|........:..||:.|..:|.:....|.
  Rat   439 PRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKN- 502

  Fly   247 PPYKPIQHDTSSDSCS----------SPEKE--IDSTMNSATTSATIIKITSS------------ 287
              |..:|     ..|.          |||.:  |::.:......|.:.:.|..
  Rat   503 --YLALQ-----SYCKMSLQEREKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRP 560

  Fly   288 -SGSAGGSSNVLNASSSAGISA------GSSSGSGVSSSAKQRK 324
             :.||.....::..:...|||.      .|.:.|.|....|.::
  Rat   561 LTSSASAIRKLMRKAELMGISTDIFPVDNSDTSSSVDGRRKHKQ 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	17/57 (30%)
Alh	NP_001262332.1	ePHD_AF10_like	118..233	CDD:277142	47/115 (41%)
Phf14	XP_006236166.1	PHD1_PHF14	313..369	CDD:277036	17/66 (26%)
		ePHD_PHF14	377..490	CDD:277144	47/115 (41%)
		PHD2_PHF14	719..768	CDD:277037
		PHD3_PHF14	862..920	CDD:277038
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566217at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010