Protein Alignment Alh and CG15439

DIOPT Version :10

• Sequence 1: NP_001262332.1
• Gene: Alh / 40850
• FlyBaseID: FBgn0261238
• Length: 1717
• Species: Drosophila melanogaster
• Sequence 2: NP_608836.1
• Gene: CG15439 / 33651
• FlyBaseID: FBgn0031606
• Length: 1008
• Species: Drosophila melanogaster
• Alignment Length: 898
• Identity: 200/898 - (22%)
• Similarity: 303/898 - (33%)
• Gaps: 303/898 - (33%)

  Fly    61 CCVCSDERGWPENPLVYCDGQNCTVAVHQACYGI----------VTVPTGPWYCRKCESQERTSR 115
            ||||..||....|.:|.||  :|.|:||:.|||:          .|..|.||:|..|.:  ..|.
  Fly   121 CCVCLGERSDDVNEIVECD--SCGVSVHEGCYGVSDNVSISSTNSTCSTEPWFCEACRA--GVSE 181

  Fly   116 VRCELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERY-SKTCYICQEI 179
            ..|||||::.|..|:||...|.|::||||:|.|.||.|..:..:.|..:...:: :|.|.:|:
  Fly   182 PDCELCPNKGGIYKETDVGKWVHLICALYVPGVAFGEVEQLSSVTLFEMQYSKWGAKVCSLCE-- 244

  Fly   180 GKPNR--ANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNV--KYCGYCQHHYSK---L 237
               |.  |..|.|:.|:...||..|||||||..|.|.|  .::.|:.  .:..:|:.|..|   .
  Fly   245 ---NALFARTGVCIGCDAGMCKTYFHVTCAQVAGFLIE--AHHEDDAADPFYAHCKVHSEKEMIK 304

  Fly   238 KKGGNVKTI----------------------PPYKP-----------IQH--------------- 254
            |:..|..|:                      |...|           |||
  Fly   305 KRRRNYHTLRLNMMQRAREKEALAAEHETPAPHPNPAQARIQRKLLKIQHKYTRHKELKPTPWVP 369

  Fly   255 --------DTSSDSCSS--PEKEI-----------DSTMNSAT--------TSATIIKIT----- 285
                    .||:.:|..  .:.||           ::.:|:.|        ..|..::.|
  Fly   370 TQKMSRLLTTSASACRRLLAKAEIMSVDVQHLEQREAHINALTDIRKKWHIAPAFSVEFTAYYMD 434

  Fly   286 ----------------SSSGSAGGSSNVLNASSSAGISAGSSSGSGVSSSAKQRKSNASSKSSSS 334
                            |.:.......:||.|.              ..::.::||:..::|.|..
  Fly   435 RIVRMDDFRQQQRELISHNAILSKDQDVLRAQ--------------YDTALEERKAVKATKDSLL 485

  Fly   335 SSSSSSSSTGG--APN-----------------PSSS---------SVHSGSASNMTGG---GSV 368
            :|..|..:..|  |||                 |.:|         ||.:.:|..|..|   |.:
  Fly   486 TSIKSLHTALGQIAPNMTLPSVDLIAHPLPEAPPKTSTPTPPQRPISVPTAAALKMGVGFPLGHL 550

  Fly   369 LPGSSNIGNISNSLNNNLPGGSSSTSSAG--NVPGGSGGIISASSG------------------- 412
            .|..|.:.: |..|:.:...|..|||||.  ..|..|.||...|..
  Fly   551 GPPGSKMDS-SRMLSTHAKQGKHSTSSASVEAAPSVSCGICKRSKDQHLLVKCDTCNLHYHLGCL 614

  Fly   413 GATQSTSSQSSTAPGTTKSSASSSSSSSNSYKEKHSKSLSKSTSSKDKDG--------------- 462
            ....:...:.|...|...|.....|..|::..| .|....||.:..:|||
  Fly   615 NPPLTRPPKKSKQYGWQCSECCDKSEGSDAVTE-ISSGPRKSRTRFNKDGHLVYVDRYSLDDIPV 678

  Fly   463 ------KDSSTNSANNNFTNSSASSTSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSSINT 521
                  |:|.|..|.|.  :..|.:.......|:.....||       |.|..|       .||.
  Fly   679 AAVNVPKESHTKRALNK--SLPAPAPEYIEDLTKSPKRPKL-------QSPCKT-------PINV 727

  Fly   522 QPSSSTSTATAGSGGTGTHVSSSAASGLNSAPSTTNEHSNHAHTLSTNGTGAGSAAGKLQSVSNL 586
            ...:.|.|..|..      |::|||:     |:.       |.||.|..|...:.:|...|:.:.
  Fly   728 PAENVTPTTDAAP------VAASAAT-----PAA-------APTLPTPNTIVINLSGCEDSIDDS 774

  Fly   587 SN--SSSGFGSDLRSVSTSSSSTVNDSTGGFGSNSNSERENLSGAGSSASNMPGTIAPGTGGVSS 649
            |.  |..|...|......:.||....|.|........:|.:|                      .
  Fly   775 SGKLSRKGKRKDKHKNKHNLSSDTEKSIGKEHKRKRKKRAHL----------------------D 817

  Fly   650 SAATNLSTNKGGSSSSTANSLTSTSTSSGSSSNSS-------SKKRKADSAKSTSSISTSGSALE 707
            .::|:|. |.|.:|.||...:.......|..:..|       :..|..|.|...:|:.|    :|
  Fly   818 ESSTHLD-NAGNTSGSTIKIIFKALRLPGEDAPESQYFYVPANAVRSVDEASRPTSVET----VE 877

  Fly   708 DNNSLISRYDIKDVQVALTPLTDFEKEIEKSSKRQRTELSPPTHQTSATAEVN 760
            |:        ::..:.||.|:.     :..:|.::..|    ..:|:|:|.||
  Fly   878 DS--------VQGAEQALAPIV-----LPAASPQKVRE----PKETAASASVN 913

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	22/55 (40%)
		ePHD_AF10_like	118..233	CDD:277142	43/119 (36%)
		CC_AF10	1636..1699	CDD:411015
CG15439	NP_608836.1	PHD1_PHF14	120..175	CDD:277036	22/55 (40%)
		ePHD_PHF14	184..297	CDD:277144	43/119 (36%)
		PHD2_PHF14	586..635	CDD:277037	7/48 (15%)
		PRK10819	854..>938	CDD:236768	17/81 (21%)
		PHD3_PHF14	949..997	CDD:277038