DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alh and Brd1

DIOPT Version :9

Sequence 1:	NP_001262332.1	Gene:	Alh / 40850	FlyBaseID:	FBgn0261238	Length:	1717	Species:	Drosophila melanogaster
Sequence 2:	XP_006242256.1	Gene:	Brd1 / 315210	RGDID:	1311855	Length:	1189	Species:	Rattus norvegicus

Alignment Length:	266	Identity:	94/266 - (35%)
Similarity:	132/266 - (49%)	Gaps:	50/266 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AKLEL--DSSKDDTIHSTSLNKKLVKIKKF---------KLDDMKEMV---GGCCVCSDERGWPE 72
            |.||:  :..|.|.:.:.|.|.....:.:|         |..:.:.::   ..||:|.|......
  Rat   164 AWLEIINEKRKGDCVSAVSQNMFEFLMDRFEKESYCENQKQGEHQSLIDEDAVCCICMDGECQNS 228

  Fly    73 NPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSRVRCELCPSRDGALKKTDNSGWA 137
            |.:::||  .|.:||||.|||:..:|.|.|.||.| .|.|.....|.|||::.||.||||:..|.
  Rat   229 NVILFCD--MCNLAVHQECYGVPYIPEGQWLCRHC-LQSRARPADCVLCPNKGGAFKKTDDDRWG 290

  Fly   138 HVVCALYIPEVRFGNVTTMEPII-LSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQ 201
            ||||||:||||.|.|...:|||. :..||..|:..|||:|::.|      ||||:||:|:||...
  Rat   291 HVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQKG------VGACIQCHKANCYTA 349

  Fly   202 FHVTCAQSLGLLCE-------EAGNYLDNVKYCGYCQHH------------YSKL-------KKG 240
            |||||||..||..:       ..|:...:|:...||..|            |..:       :|.
  Rat   350 FHVTCAQKAGLYMKMEPVKELTGGSTTFSVRKTAYCDVHTPPGCTRRPLNIYGDVEMKNGVCRKE 414

  Fly   241 GNVKTI 246
            .:|||:
  Rat   415 SSVKTV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	20/46 (43%)
Alh	NP_001262332.1	ePHD_AF10_like	118..233	CDD:277142	56/122 (46%)
Brd1	XP_006242256.1	EPL1	47..196	CDD:287484	8/31 (26%)
		PHD_BRPF2	214..267	CDD:277147	23/55 (42%)
		ePHD_BRPF2	271..388	CDD:277172	56/122 (46%)
		Bromo_brd1_like	566..663	CDD:99944
		BR140_related	1058..1173	CDD:99900
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566217at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920