DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alh and Kdm4b

DIOPT Version :9

Sequence 1:	NP_001262332.1	Gene:	Alh / 40850	FlyBaseID:	FBgn0261238	Length:	1717	Species:	Drosophila melanogaster
Sequence 2:	XP_030105461.1	Gene:	Kdm4b / 193796	MGIID:	2442355	Length:	1124	Species:	Mus musculus

Alignment Length:	228	Identity:	69/228 - (30%)
Similarity:	110/228 - (48%)	Gaps:	36/228 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 NPLVYCDGQNCTVAVHQACYGI-VTVPTGPWYCRKCESQERTSRVRCELCPSRDGALKKTDNSGW 136
            :||:.|  .:|.:.||.:|||: ..:....|.|.:|.:...|:  .|.||..|.|||::|....|
Mouse   781 SPLISC--AHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTA--ECCLCNLRGGALQRTTEHRW 841

  Fly   137 AHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCYICQEIGKPNRANVGACMQCNKSNCKQQ 201
            .||:||:.:|||||.||....|:.:|.||::|:...|..|::  :..|.: |||:||:..:|...
Mouse   842 IHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRK--RMKRVS-GACIQCSYEHCSTS 903

  Fly   202 FHVTCAQSLGLLCE-EAGNYLDNVKYCGYCQHHYSKLKKGGNVKTIPPYKPIQHDTSSDSCSSPE 265
            ||||||.:.|:|.| :...|:.::.    |..|.:....|..::|:               |..:
Mouse   904 FHVTCAHAAGVLMEPDDWPYVVSIT----CLKHRASGAGGQLLRTV---------------SLGQ 949

  Fly   266 KEIDSTMNS--------ATTSATIIKITSSSGS 290
            ..|....|.        .||:.|..::....||
Mouse   950 IVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGS 982

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	11/34 (32%)
Alh	NP_001262332.1	ePHD_AF10_like	118..233	CDD:277142	45/115 (39%)
Kdm4b	XP_030105461.1	JmjN	15..56	CDD:128818
		JmjC	176..292	CDD:334913
		PHD_SF	680..814	CDD:389947	11/34 (32%)
		PHD_SF	823..932	CDD:389947	45/115 (39%)
		Tudor_2	948..982	CDD:375553	5/33 (15%)
		Tudor_2	1006..1040	CDD:375553
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910