Protein Alignment Alh and mllt10

DIOPT Version :9

• Sequence 1: NP_001262332.1
• Gene: Alh / 40850
• FlyBaseID: FBgn0261238
• Length: 1717
• Species: Drosophila melanogaster
• Sequence 2: XP_012821091.1
• Gene: mllt10 / 100036598
• XenbaseID: XB-GENE-6408100
• Length: 1025
• Species: Xenopus tropicalis
• Alignment Length: 1187
• Identity: 341/1187 - (28%)
• Similarity: 500/1187 - (42%)
• Gaps: 299/1187 - (25%)

  Fly    54 MKEMVGGCCVCSDERGWPENPLVYCDGQNCTVAVHQACYGIVTVPTGPWYCRKCESQERTSRVRC 118
            ||||:||||||||||||.|||||||||..|.|||||||||||.||||||:|||||||||.:||||
 Frog    19 MKEMIGGCCVCSDERGWAENPLVYCDGHGCNVAVHQACYGIVQVPTGPWFCRKCESQERAARVRC 83

  Fly   119 ELCPSRDGALKKTDNSGWAHVVCALYIPEVRFGNVTTMEPIILSLIPQERYSKTCYICQEIGKPN 183
            ||||.:|||||:|||.||||||||||||||:|.||:|||||:|..:|.|||:||||||.|.|:.:
 Frog    84 ELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHERYNKTCYICDEQGRES 148

  Fly   184 RANVGACMQCNKSNCKQQFHVTCAQSLGLLCEEAGNYLDNVKYCGYCQHHYSKLKKGGNVKTIPP 248
            :|..||||.|||..|:|.|||||||..||||||.||..|||:|||||::||||||.....|
 Frog   149 KAATGACMTCNKHGCRQAFHVTCAQLAGLLCEEEGNGADNVQYCGYCKYHYSKLKHKEKEK---- 209

  Fly   249 YKPIQHDTSSDSCSSPEKEIDSTMNSATTSATIIKITSSSGSAGGSSNVLNASSSAGISAGSSSG 313
                 |...|.....|...:..:: :.||..|   .|.||                     |::.
 Frog   210 -----HRQKSRKQMEPLPALVPSL-TVTTEKT---YTCSS---------------------SNNN 244

  Fly   314 SGVSSSAKQ------RKSNASSKSSSSSSSSSSSSTGGAPNPSSSSVHSGSASNMTGGGSVLPGS 372
            :.|.||.|:      |.:||:.:..|:..:|...:....   ||......:||::|
 Frog   245 NSVPSSVKRIEDTSARFTNANFQEVSTHPTSVKEALEAR---SSEIKGKKAASHIT--------- 297

  Fly   373 SNIGNISNSLNNNLPGGSSSTSSAGNVPGGSGGIISASSGGATQSTSSQSSTAPGTTKSSASSSS 437
                         |..|..|:|...            .:|.||.::..|.:...||..|..|||.
 Frog   298 -------------LQRGRKSSSGRN------------CAGSATATSPFQQAHFSGTPSSVKSSSG 337

  Fly   438 SSSNSYKE--------------KHSKSLSKSTSSKDKDGKDSS----------------TN---- 468
            ||..|.:|              .||:.|   ||:||....|:.                ||
 Frog   338 SSVQSPQEFLSFTEFEVRTESYHHSQQL---TSTKDAPKGDTGLQEGTINSFSSLIGLPTNPPLS 399

  Fly   469 -------SANNNFTNSSAS--------STSSNSSSTREKSSSKLSKNKDSNQVPSATSSLSTTSS 518
                   |...::.|||.:        |:..:..:.:||......:||.....|....:..|.|.
 Frog   400 FQTKNYESVPGDYVNSSLTVAGYKRLQSSVLDEDTVKEKKRKGNKQNKHGPGRPKGNKNQETLSH 464

  Fly   519 INTQPSSSTSTATAGSGGTGTHVSSSAASGLNSAPSTTNEHSNHAHTLSTNGTGAGSAAGKLQSV 583
            ::...:|.||:..:.:|       |.|:|.:..:|           ||..||           |:
 Frog   465 LSASSASPTSSVASAAG-------SIASSVIQRSP-----------TLLRNG-----------SL 500

  Fly   584 SNLSNSSSGFGSDLRSVSTSSSSTVNDSTGGFGSNSNSERENLSGAGS--SASNMPGTIAPGTGG 646
            .:||..||..||       :|....||....|.|       .|||:.:  |:|::|...|.....
 Frog   501 QSLSVGSSPGGS-------ASLCNCNDVPTSFPS-------ALSGSSTPVSSSHIPQPAAAHLQQ 551

  Fly   647 VSSSAATNLSTNKGGSSSSTANSLTSTSTSSGSSSNSSSKKRKADSAKSTSSISTSGSALEDNNS 711
            ..||:.::|:|....:.::..:||..:|.:. |||::..::....||..|..: .|.:|..|.::
 Frog   552 EVSSSPSSLATVPANTVATQVSSLPGSSLAM-SSSHTYGRRLNPTSAAGTLPV-PSENAQPDQDA 614

  Fly   712 LISRYDIKDVQVALTPLTDFEKEIEKSSKRQRTELSPPTHQTSATAEVNAPLASSTSASIAVTAS 776
            :                 |..:.:.......|..:||..:.....::..:||.|..::....:.:
 Frog   615 V-----------------DHNRNLPAKGASPRGSISPRLNIYGVGSDKISPLNSLATSRFEPSGN 662

  Fly   777 ATAASAPPATGTTTLGSSI-----SGNAGSTSSGNSSGV----------------------SATG 814
            ::..|.|||  .|::...:     .|.......|.||.:                      :.|.
 Frog   663 SSLESVPPA--ATSIEQLLERQWSEGQQFLQEQGTSSDILGMLKSLHQLQVENRRLEEQIKNLTA 725

  Fly   815 --------GAQSAVGSGGYPKTESSKSSGTASAGSGSGSSSNTSSTKHGSNIKDISSSSNQQAST 871
                    .||.:|   .:|         |.|      |:.|||...|...::::|:|.:...|.
 Frog   726 KKERLQLLNAQLSV---PFP---------TIS------SNPNTSPQVHTYPLQNVSNSDSLNISK 772

  Fly   872 ASSSSAPSLYVSVPLSTANVPGINLPTSSTSSSTTSES------------HSASSRSSGAQSQHQ 924
            :.......|..::|:....:......|||:||.:|...            |..:..:.||.:...
 Frog   773 SPHLGNFQLDNALPVPNQELTSSGQSTSSSSSLSTPPPDGQSPAQQVQGVHRINGVAMGALTSGI 837

  Fly   925 QQLSNALVGPPMGGSAGAFHGG------TTSAGSSSVIQQQSGKSSPALGTLVSGNSGGSIISAS 983
            |.::.||   |...|.||..|.      :.:.|:.:.:.|     :||.....:..:.|||:...
 Frog   838 QSVTQAL---PNVASVGAIIGALPANQLSINFGALNGVMQ-----NPANLPQTAALTHGSILPNV 894

  Fly   984 GFPLPSGNLTATTTESGNLKISYEKQTTRVQQLQEQEAPPARRSRSRSGESGSSHHHAHAH---- 1044
            ..|:.|    :....:..|.:..::|...:...|:|:......|:..:.|    .||...:
 Frog   895 THPITS----SLANSASGLGLLTDQQRQLLLHQQQQQFQHILNSQQLTPE----QHHTFLYQLMQ 951

  Fly  1045 -HHHHHPTHHNSHHQQNPQQQQQLHQQQQQNASSHMHACTNSSSSTSTSTTSSSLSGGTAPATSS 1108
             ||.....||     |...||.|:....|...:|.:.....:...::|:....:|.|.||
 Frog   952 QHHQQQQQHH-----QPELQQLQIPGAAQLPLNSLLAGAQAAPLHSTTTNPFLALHGDTA----- 1006

  Fly  1109 SNSKGPSRSGKKRGAAM 1125
              ::..||.|.|.|..:
 Frog  1007 --AQKVSRLGDKSGPVL 1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alh	NP_001262332.1	PHD_AF10_AF17	60..107	CDD:277049	40/46 (87%)
		ePHD_AF10_like	118..233	CDD:277142	81/114 (71%)
mllt10	XP_012821091.1	PHD_AF10_AF17	25..72	CDD:277049	40/46 (87%)
		ePHD_AF10	79..207	CDD:277178	90/127 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I3065
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2092
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004366
OrthoInspector	1	1.000	-	-		otm47725
Panther	1	1.100	-	-	LDO	PTHR13793
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3088
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.150