DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and csrp1b

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001074083.1	Gene:	csrp1b / 791132	ZFINID:	ZDB-GENE-070112-252	Length:	192	Species:	Danio rerio

Alignment Length:	183	Identity:	97/183 - (53%)
Similarity:	120/183 - (65%)	Gaps:	4/183 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYCKTCHGRKFGPKGYGF 75
            ||..|.|:||.|||....|..|||:||.|.:|.|:||||....|:.|:|||:|:|:|:|||||||
Zfish     8 KCGCCKKTVYFAEEVQCEGQSFHKSCFLCMVCRKNLDSTTVAVHQDEIYCKSCYGKKYGPKGYGF 72

  Fly    76 GTGAGTLSMDNGSQF-LRENGDVPSVRNGARLEPRAIARAPEG-EGCPRCGGYVYAAEQMLARGR 138
            |.||||||||.|... :|..|:. |.|......|...|:...| :.|||||..|:|||:::..|.
Zfish    73 GGGAGTLSMDGGEALGIRPAGET-SHRPTNNPNPSKFAQKLGGSDVCPRCGNAVFAAEKVVGGGN 136

  Fly   139 SWHKECFKCGTCKKGLDSILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGGGAL 191
            ||||.||:|..|.|.|:|....: .|..|||||||||.|||||:|:|||.|||
Zfish   137 SWHKSCFRCAKCGKSLESTTLAD-KDGEIYCKGCYAKNFGPKGFGFGQGAGAL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	27/52 (52%)
		LIM_CRP_like	120..173	CDD:188712	27/52 (52%)
		LIM_CRP_like	222..275	CDD:188712
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
csrp1b	NP_001074083.1	LIM	7..62	CDD:295319	28/53 (53%)
csrp1b	NP_001074083.1	LIM2_CRP	118..171	CDD:188787	28/53 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575192
Domainoid	1	1.000	79	1.000	Domainoid score	I8580
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	1	1.000	-	-		otm25288
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24215
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.810