DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mlp84B and crip2

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_012824147.1	Gene:	crip2 / 780192	XenbaseID:	XB-GENE-953187	Length:	220	Species:	Xenopus tropicalis

Alignment Length:	206	Identity:	76/206 - (36%)
Similarity:	98/206 - (47%)	Gaps:	28/206 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 APKCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYC-KTCHGRKFGPKG 72
            |.|||:|.|:||.||:..:.|..:||.|.||..|||:|:.....||:.:.|| |.|:...:||||
Frog     2 ASKCPKCDKTVYFAEKVTSLGKDWHKFCLKCERCNKTLNPGGHAEHDGKPYCHKPCYAALYGPKG 66

  Fly    73 YGFGTGAGTLSMDN---------------GSQFLRENGDVP--SVRNGARLEPRAIARAPE---- 116
            ...| |||:...|.               .|...:.:|..|  |:..||:..|.|...|..
Frog    67 VNIG-GAGSYIYDRKPSEDKPTSPTEVQPKSDERKVSGPAPIRSLSKGAQGSPPADITASSITTF 130

  Fly   117 -GEG--CPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDSILCCEAPDKNIYC-KGCYAKKF 177
             ||.  ||||...||.||::.:.|:.||:.|.:|..|.|.|......| .|...|| |.||...|
Frog   131 TGEPNLCPRCAQKVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGSHAE-HDGQPYCHKPCYGILF 194

  Fly   178 GPKGYGYGQGG 188
            ||||...|..|
Frog   195 GPKGVNTGGVG 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	24/53 (45%)
		LIM_CRP_like	120..173	CDD:188712	21/53 (40%)
		LIM_CRP_like	222..275	CDD:188712
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
crip2	XP_012824147.1	LIM1_TLP	5..58	CDD:188860	23/52 (44%)
crip2	XP_012824147.1	LIM1_TLP	137..190	CDD:188860	21/53 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010