DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and Crip2

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_077185.1	Gene:	Crip2 / 68337	MGIID:	1915587	Length:	208	Species:	Mus musculus

Alignment Length:	216	Identity:	75/216 - (34%)
Similarity:	100/216 - (46%)	Gaps:	43/216 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 APKCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYC-KTCHGRKFGPKG 72
            |.|||:|.|:||.||:..:.|..:||.|.||..|||:|......||:.:.:| |.|:...|||||
Mouse     2 ASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKG 66

  Fly    73 YGFGTGAGTLSMDN-GSQFLRENG--DVPSVRNGARLEPRAIARAPEGEG--------------C 120
            ...| |||:...:. .::..:..|  :||.||.    |.|..:..|:|..              |
Mouse    67 VNIG-GAGSYIYEKPQTEAPQVTGPIEVPVVRT----EERKTSGPPKGPSKASSVTTFTGEPNMC 126

  Fly   121 PRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLDSILCCEAP------DKNIYC-KGCYAKKFG 178
            |||...||.||::.:.|:.||:.|.:|..|.|.|       .|      |...|| |.||...||
Mouse   127 PRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTL-------TPGGHAEHDGQPYCHKPCYGILFG 184

  Fly   179 PKGYGYGQGGGALQSDCYAHD 199
            |||...|..|.      |.:|
Mouse   185 PKGVNTGAVGS------YIYD 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	23/53 (43%)
		LIM_CRP_like	120..173	CDD:188712	21/59 (36%)
		LIM_CRP_like	222..275	CDD:188712
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
Crip2	NP_077185.1	LIM1_TLP	5..58	CDD:188860	22/52 (42%)
Crip2	NP_077185.1	LIM1_TLP	126..179	CDD:188860	21/59 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820