DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and lima1a

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_571739.1	Gene:	lima1a / 64000	ZFINID:	ZDB-GENE-001120-1	Length:	629	Species:	Danio rerio

Alignment Length:	329	Identity:	76/329 - (23%)
Similarity:	110/329 - (33%)	Gaps:	109/329 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KNCFKCGMCNKSLDSTNCTEHERELYCKTCHGRKFGPKGYGFGTGAGTLSMDNGSQFLRENGDVP 98
            |...:||:  |.||||...: ...:|........| |...............:|.|  :||  ||
Zfish   184 KESLECGV--KMLDSTPLRD-RMAMYQAAVTKLDF-PSSPNSEAADSEARAHSGKQ--KEN--VP 240

  Fly    99 SV-----------------RNGARLEPR-------AIARAPEGEGCPRCGGYVYAAEQMLARGRS 139
            .|                 |||:.|.|.       .:...|..|.|..|...||..|:::|..:.
Zfish   241 PVSADVCPESNTIKSPAPDRNGSVLSPEQNQPKLVKMFPLPVRETCVTCLKTVYPLEKLVANQQI 305

  Fly   140 WHKECFKCGTCKKGLDSILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGGGALQSDCYAHD----- 199
            :|..||:|..|...| |::...:...|:|||..|.:.|..|| .|.:|        :.|.
Zfish   306 YHNTCFRCAYCNTKL-SLVNYASLHNNVYCKPHYCQLFKAKG-NYDEG--------FGHRPHKEL 360

  Fly   200 -DGAPQIRAAIDVDKIQARPG------EGCPRCGGVVYAA-------------EQKLSKGR---E 241
             :|.|:   .:| |:::..|.      |..|.....|.||             |:.|..||   .
Zfish   361 WEGRPE---GVD-DQVKLSPQETSLTVEESPLVKVNVLAATLETRTQATSERVEKPLETGRLKIS 421

  Fly   242 WHKKCFNCKDCHKTLDSINASDG----PDRDVYCRTCYGKKWGPHGYGFACGSGFLQTDGLTEDQ 302
            |..:....:....|:     :||    |.|         .||.|.|                 |.
Zfish   422 WPPQSEGDESATHTV-----TDGSGIKPIR---------PKWPPEG-----------------DT 455

  Fly   303 ISAN 306
            :|:|
Zfish   456 VSSN 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	9/29 (31%)
		LIM_CRP_like	120..173	CDD:188712	17/52 (33%)
		LIM_CRP_like	222..275	CDD:188712	14/72 (19%)
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
lima1a	NP_571739.1	LIM_Eplin_alpha_beta	286..338	CDD:188869	17/52 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910