DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and csrp3

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001307020.1	Gene:	csrp3 / 450005	ZFINID:	ZDB-GENE-041010-119	Length:	222	Species:	Danio rerio

Alignment Length:	193	Identity:	86/193 - (44%)
Similarity:	105/193 - (54%)	Gaps:	29/193 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYCKTCHGRKFGPKGYGF 75
            ||..|.|:||.|||.......|||.||.|.:|.|.||||....||.|:|||||:|:|:||||||:
Zfish    38 KCAACEKTVYHAEEIQCNSRSFHKTCFICMVCRKGLDSTTVAAHESEIYCKTCYGKKYGPKGYGY 102

  Fly    76 GTGAGTLSMD--NGSQFLRENGDVPSVRNGARLEPRAIARAPEG-------------EGCPRCGG 125
            |.|||.||.|  |..:...:             ||:|...||..             :.||||..
Zfish   103 GQGAGALSSDPVNNEELQPQ-------------EPKAPRPAPANSNSSKFAQKFGSTDRCPRCSK 154

  Fly   126 YVYAAEQMLARGRSWHKECFKCGTCKKGLDSILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGG 188
            .|||||:::..|:.|||.||:|..|.|.|:|....: .|..:|||.||||.|||||.|.|..|
Zfish   155 AVYAAEKIMGAGKPWHKTCFRCLLCGKSLESTTVTD-KDGELYCKVCYAKNFGPKGRGLGNPG 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	28/52 (54%)
		LIM_CRP_like	120..173	CDD:188712	24/52 (46%)
		LIM_CRP_like	222..275	CDD:188712
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
csrp3	NP_001307020.1	LIM1_CRP3	38..91	CDD:188865	28/52 (54%)
csrp3	NP_001307020.1	LIM2_CRP3	149..202	CDD:188866	25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575195
Domainoid	1	1.000	79	1.000	Domainoid score	I8580
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	1	1.000	-	-		otm25288
orthoMCL	1	0.900	-	-		OOG6_104400
Panther	1	1.100	-	-	LDO	PTHR24215
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4662
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.880