DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and csrp1

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001006881.1	Gene:	csrp1 / 448688	XenbaseID:	XB-GENE-941448	Length:	193	Species:	Xenopus tropicalis

Alignment Length:	184	Identity:	98/184 - (53%)
Similarity:	120/184 - (65%)	Gaps:	6/184 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYCKTCHGRKFGPKGYGF 75
            ||..|.||||.|||....|..|||:||.|.:|.|:||||....|..|:|||:|:|:|:|||||||
Frog     9 KCTVCQKSVYFAEEVQCEGGSFHKSCFLCMVCKKNLDSTTVAIHGEEIYCKSCYGKKYGPKGYGF 73

  Fly    76 GTGAGTLSMDNGSQFLRENGDVPSVRNGARLEPRAIARAPEGEG---CPRCGGYVYAAEQMLARG 137
            |.||||||||.| :.|....|.|| |:.....|.|...|.:..|   ||||...|||||:::..|
Frog    74 GQGAGTLSMDRG-EHLGIQTDDPS-RSQPTNNPNASKFAQKVGGTDICPRCSKSVYAAEKVIGAG 136

  Fly   138 RSWHKECFKCGTCKKGLDSILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGGGAL 191
            .|||:.||:|..|.|||:|....:. |.:|:||.||||.|||||:|:|||.|||
Frog   137 NSWHRTCFRCSKCGKGLESTTVADR-DGDIFCKACYAKNFGPKGFGFGQGAGAL 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	28/52 (54%)
		LIM_CRP_like	120..173	CDD:188712	25/52 (48%)
		LIM_CRP_like	222..275	CDD:188712
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
csrp1	NP_001006881.1	LIM1_CRP1	8..63	CDD:188863	29/53 (55%)
csrp1	NP_001006881.1	LIM2_CRP	119..172	CDD:188787	26/53 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I8277
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1214165at2759
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	1	1.000	-	-		otm47886
Panther	1	1.100	-	-	O	PTHR24215
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4662
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.140