DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and mical3a

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_021323435.1	Gene:	mical3a / 402881	ZFINID:	ZDB-GENE-050126-2	Length:	2522	Species:	Danio rerio

Alignment Length:	413	Identity:	88/413 - (21%)
Similarity:	129/413 - (31%)	Gaps:	146/413 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 EQMLARGRSWHKECFKCGT-------CKKGLDSILCCEAPDKNIY------CKGCYAKKFGP--- 179
            |||..|    :||..||.|       ...|.:.:..|  |.|.|.      ....::..|.|
Zfish   807 EQMSFR----YKEKLKCQTLPITQEQASSGTEVLRSC--PKKTILLSSSSPSSSSFSSSFPPHAQ 865

  Fly   180 ----KGYGYGQGGGALQ--SDCYAHDDGAPQI--RAAIDVDKIQARPGEGCPRCGGVVYAAEQKL 236
                |..|.|.|....|  |.|| .:|..|.:  ...|.:..||.|              ||..:
Zfish   866 SVIHKCNGVGDGENRFQDLSVCY-WEDNLPNVDKPEPIHIRSIQER--------------AETLV 915

  Fly   237 S--KGREWHKKCFNCKDCHKTLDSINASDGPDRDVYCRTCYGKKWGPHGYGFACGSGFLQTDGLT 299
            :  ||:...|            |.......|.|      .:.::|            || |.||:
Zfish   916 ARFKGKADRK------------DKPQVMKKPSR------FFIEQW------------FL-THGLS 949

  Fly   300 EDQ-ISANRPFYN-------PD------TTSIKAR---------DGEGCPRC--GGAVFAAEQQL 339
            .|: :.::.|.::       ||      ..||:.|         |....|:.  ..::...||
Zfish   950 PDEPVFSSDPQHHQQKGVLCPDDHVPLHIPSIQERAERLASHFKDKPAKPKSKKKSSLLLTEQ-- 1012

  Fly   340 SKGKVWHKKCYNCADCHRPLDSVLACDGPDG-DIHCRACYGKLFGPKGFGYGHAPTLVSTSGEST 403
                 |.:.        |.:.|......|.. ..||...|          .|...:|........
Zfish  1013 -----WSRA--------RDVSSASPLHSPSSFRQHCVKMY----------TGGVSSLAEQIANQL 1054

  Fly   404 IQFPDGRPLAG-----------PKTSGGCPRCGFA---VFAAEQMISKTRIWHKRCFYCSDCRKS 454
            ....|.||:..           |:..||...|.|.   |:..|::.::.:.:|:.||.|..|..:
Zfish  1055 QAKDDPRPMLEKRDLGSFRKEFPQNIGGSDVCFFCRKRVYVMERLSAEGKFFHRSCFKCDYCGTT 1119

  Fly   455 LD-STNLNDGPDGDIYCRA--CY 474
            |. |:...|..||..||:.  ||
Zfish  1120 LRLSSYAFDVEDGKFYCKPHYCY 1142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788
		LIM_CRP_like	120..173	CDD:188712	14/54 (26%)
		LIM_CRP_like	222..275	CDD:188712	8/54 (15%)
		LIM_CRP_like	325..378	CDD:188712	9/55 (16%)
		LIM_CRP_like	421..474	CDD:188712	16/58 (28%)
mical3a	XP_021323435.1	FAD_binding_3	91..>239	CDD:332373
		CH	536..636	CDD:306753
		LIM_Mical	1086..1140	CDD:188823	16/53 (30%)
		Herpes_BLLF1	<1488..1803	CDD:330317
		DUF4045	<1840..>1896	CDD:330572
		SMC_N	<2220..>2506	CDD:330553
		DUF3585	2318..2508	CDD:314926
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910