DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and rga1

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_596743.1	Gene:	rga1 / 2541022	PomBaseID:	SPBC3F6.05	Length:	1150	Species:	Schizosaccharomyces pombe

Alignment Length:	221	Identity:	47/221 - (21%)
Similarity:	70/221 - (31%)	Gaps:	75/221 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 RNGARLEPRAIARAPEGEGCPRCGGYVYAAEQMLARGRSWHKECFKCGTCK-------------- 151
            |:...:.|:|:.:....:.|..| |.|.:.:.:.|.|..:|.|||:|..|.
pombe    97 RSDTSVFPKAVRKVSSSKICASC-GQVISGQYVRALGNIYHLECFRCHDCNSLVASKFFPIDDPT 160

  Fly   152 -------------KGLDSILCCE-----------APDKNIY-----CKGCYAKKFGPKGYGYGQG 187
                         :.|| :||..           |.:|..:     |..||. .|||....|...
pombe   161 LNKQVPLCETDYFRRLD-LLCASCGMALRGYYITALNKKFHIEHFTCSLCYT-VFGPNDSYYEYE 223

  Fly   188 GGALQSDCYAHDDGAPQIRAAIDVDKIQARPGEGCPRCGGVV---YAAEQKLSKGREWHKKC--- 246
            |...   |:.|.......|               |..|.|.:   :....:....:.||..|
pombe   224 GKVY---CHYHYSTLFAAR---------------CCGCDGPILRQFVEVYRNGVSQNWHVPCHMI 270

  Fly   247 ---FNCKDCHKTLDSINASDGPDRDV 269
               :|.|.|.||  ||..|...|.::
pombe   271 YKFWNVKLCQKT--SIETSKKKDSEL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788
		LIM_CRP_like	120..173	CDD:188712	19/95 (20%)
		LIM_CRP_like	222..275	CDD:188712	15/57 (26%)
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
rga1	NP_596743.1	LIM1_Lrg1p_like	116..172	CDD:188777	12/56 (21%)
		LIM2_Lrg1p_like	180..232	CDD:188778	12/55 (22%)
		LIM	485..539	CDD:295319
		RhoGAP_fLRG1	835..1044	CDD:239862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24215
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100