DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and Mical3

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	XP_036021853.1	Gene:	Mical3 / 194401	MGIID:	2442733	Length:	2252	Species:	Mus musculus

Alignment Length:	349	Identity:	65/349 - (18%)
Similarity:	105/349 - (30%)	Gaps:	125/349 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 PEGEG----CPRCGGYVYAAEQMLARGRSWHKECFKCGTCKKGLD-SILCCEAPDKNIYCKGCYA 174
            |:..|    |..|...||..|::.|.|:.:|:.||||..|...|. |....:..|...|||..|.
Mouse   907 PQNLGGSDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYC 971

  Fly   175 KKFGPKGYGYGQ---------GG----GALQSDCYAHDDGAPQI--------------------- 205
            .:..    ||.|         .|    ||||....|..:|...:
Mouse   972 YRLS----GYAQRKRPAVAPLSGKEVKGALQDGPTADANGLASVAASSAERSPGTSMNGLEEPSI 1032

  Fly   206 -----------------RAAIDVDKIQARPGEGCPRCGGVVYAAEQKLS----KGREWHKKCFNC 249
                             |:...|::::..|.|         ..||..||    ||.|   :....
Mouse  1033 AKRLRGTPERIELENYRRSVRQVEELEEVPEE---------TQAEHNLSSVLDKGTE---EDVAS 1085

  Fly   250 KDCHKTLDSINASDGPDRDVYCRTCYGKKWGP----HGYGFACGSGFLQTDGLTEDQISANRPF- 309
            ......::.....|..|..:......|..|..    |..          ..|.:|:::.|::.|
Mouse  1086 SSSESEMEEEEEEDDEDDHLPTSDLGGVPWKEAVRIHAL----------LKGRSEEELEASKNFE 1140

  Fly   310 ----------------YNPDTTSIKARDGEGCPRCGGAVFAAEQQLSKGKVW------HKKCYNC 352
                            |..:.....:.:||.||        .:::|.:|: |      .::...|
Mouse  1141 PEEEEEEEEYEEEDEEYEEEEEEESSEEGEYCP--------WDRELLQGQ-WLQHLSKEEEMGTC 1196

  Fly   353 ADCHRPLDSVLACDGP---DGDIH 373
            ...::.|..::....|   ..|:|
Mouse  1197 EAGNKRLQQIITAADPLAIQADVH 1220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788
		LIM_CRP_like	120..173	CDD:188712	19/53 (36%)
		LIM_CRP_like	222..275	CDD:188712	9/56 (16%)
		LIM_CRP_like	325..378	CDD:188712	10/58 (17%)
		LIM_CRP_like	421..474	CDD:188712
Mical3	XP_036021853.1	FAD_binding_3	87..>274	CDD:396193
		CH_MICAL3	515..625	CDD:409100
		LIM_Mical	916..970	CDD:188823	19/53 (36%)
		PHA03307	1280..>1709	CDD:223039
		DUF3585	2065..2233	CDD:403377
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810