DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mlp84B and Csrp1

DIOPT Version :9

Sequence 1:	NP_001303418.1	Gene:	Mlp84B / 40849	FlyBaseID:	FBgn0014863	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001347711.1	Gene:	Csrp1 / 13007	MGIID:	88549	Length:	193	Species:	Mus musculus

Alignment Length:	182	Identity:	94/182 - (51%)
Similarity:	117/182 - (64%)	Gaps:	2/182 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KCPRCGKSVYAAEERLAGGYVFHKNCFKCGMCNKSLDSTNCTEHERELYCKTCHGRKFGPKGYGF 75
            ||..|.|:||.|||....|..|||:||.|.:|.|:||||....|..|:|||:|:|:|:||||||:
Mouse     9 KCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKSCYGKKYGPKGYGY 73

  Fly    76 GTGAGTLSMDNGSQFLRENGDVPSVRNGARLEPRAIARAPEG-EGCPRCGGYVYAAEQMLARGRS 139
            |.||||||.|.|.....::.:.|..|..........|:...| |.||||...|||||:::..|:|
Mouse    74 GQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCPRCSQAVYAAEKVIGAGKS 138

  Fly   140 WHKECFKCGTCKKGLDSILCCEAPDKNIYCKGCYAKKFGPKGYGYGQGGGAL 191
            |||.||:|..|.|||:|....: .|..|||||||||.|||||:|:|||.|||
Mouse   139 WHKSCFRCAKCGKGLESTTLAD-KDGEIYCKGCYAKNFGPKGFGFGQGAGAL 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mlp84B	NP_001303418.1	LIM1_MLP84B_like	11..64	CDD:188788	27/52 (52%)
		LIM_CRP_like	120..173	CDD:188712	28/52 (54%)
		LIM_CRP_like	222..275	CDD:188712
		LIM_CRP_like	325..378	CDD:188712
		LIM_CRP_like	421..474	CDD:188712
Csrp1	NP_001347711.1	LIM1_CRP1	8..63	CDD:188863	28/53 (53%)
		Nuclear localization signal. /evidence=ECO:0000255	64..69		2/4 (50%)
		LIM2_CRP	119..172	CDD:188787	29/53 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832341
Domainoid	1	1.000	79	1.000	Domainoid score	I8633
eggNOG	1	0.900	-	-		E2759_KOG1700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000284
OrthoInspector	1	1.000	-	-		otm42781
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24215
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4662
SonicParanoid	1	1.000	-	-		X318
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.830