Protein Alignment alphaTub84B and TUBA1C

DIOPT Version :10

• Sequence 1: NP_476772.1
• Gene: alphaTub84B / 40848
• FlyBaseID: FBgn0003884
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_001290043.1
• Gene: TUBA1C / 84790
• HGNCID: 20768
• Length: 519
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 434/449 - (96%)
• Similarity: 443/449 - (98%)
• Gaps: 1/449 - (0%)

  Fly     2 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAV 66
            ||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||
Human    72 RECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAV 136

  Fly    67 FVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTG 131
            ||||||||:|||||||||||||||||||||||||||||||||||||||:||||||||||||||||
Human   137 FVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTG 201

  Fly   132 LQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLE 196
            |||||:||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||
Human   202 LQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLE 266

  Fly   197 HSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVP 261
            |||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||
Human   267 HSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVP 331

  Fly   262 YPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPK 326
            ||||||||.||||||||||||||||:|||||||||||||||||||||||||||||:|||||||||
Human   332 YPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPK 396

  Fly   327 DVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL 391
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||
Human   397 DVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARL 461

  Fly   392 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAEEY 450
            |||||||||||||||||||||||||||||||||:|||||||||||.||.|||.|| |||
Human   462 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEG-EEY 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84B	NP_476772.1	PTZ00335	1..439	CDD:185562	424/436 (97%)
TUBA1C	NP_001290043.1	PTZ00335	72..518	CDD:185562	431/446 (97%)