DRSC/TRiP Functional Genomics Resources

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Protein Alignment alphaTub84B and TUBA4B

DIOPT Version :9

Sequence 1:NP_476772.1 Gene:alphaTub84B / 40848 FlyBaseID:FBgn0003884 Length:450 Species:Drosophila melanogaster
Sequence 2:NP_001342150.1 Gene:TUBA4B / 80086 HGNCID:18637 Length:241 Species:Homo sapiens


Alignment Length:223 Identity:167/223 - (74%)
Similarity:182/223 - (81%) Gaps:23/223 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 GTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGT 145
            |||||:||||||||||||||||||.||||||||.:||:||||||||||||||||||:|||.|.||
Human    20 GTYRQIFHPEQLITGKEDAANNYAWGHYTIGKEFIDLLLDRIRKLADQCTGLQGFLVFHSLGRGT 84

  Fly   146 GSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIY 210
            ||..||.|||.|||:|||||||.|:||||||||||:|:|||||||||||||||||||||||:|||
Human    85 GSDVTSFLMEWLSVNYGKKSKLGFSIYPAPQVSTAMVQPYNSILTTHTTLEHSDCAFMVDNKAIY 149

  Fly   211 DICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV-------PYPRIHFP 268
            |||..||||||||||||||||.||||||||||||||||||||||||||||       |:|.:|  
Human   150 DICHCNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVSYLTSTSPWPPMH-- 212

  Fly   269 LVTYAPVISAEKAYHEQLSVAEITNACF 296
                  ..|.:|.|        .|::|:
Human   213 ------QSSLQKRY--------TTSSCW 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alphaTub84BNP_476772.1 PTZ00335 1..439 CDD:185562 167/223 (75%)
TUBA4BNP_001342150.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20 167/223 (75%)
Tubulin 20..>207 CDD:330767 159/186 (85%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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