Protein Alignment alphaTub84B and TUBA8

DIOPT Version :10

• Sequence 1: NP_476772.1
• Gene: alphaTub84B / 40848
• FlyBaseID: FBgn0003884
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_061816.1
• Gene: TUBA8 / 51807
• HGNCID: 12410
• Length: 449
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 408/448 - (91%)
• Similarity: 422/448 - (94%)
• Gaps: 0/448 - (0%)

  Fly     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRA 65
            ||||||:||||||||||||||||:|||||||.||...:..:....||||.|||||||.|||||||
Human     1 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGKHVPRA 65

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCT 130
            |.:|||||||||||.|||||||||||||||||||||||||||||:|||.:||||||||||.|.|:
Human    66 VMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACS 130

  Fly   131 GLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTL 195
            ||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||
Human   131 GLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            ||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||
Human   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   261 PYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVP 325
            ||||||||||||||:|||||||||||||||||::||||.:|||||||||||||||||||||||||
Human   261 PYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVP 325

  Fly   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            ||||.|||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Human   326 KDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAE 448
            ||||||||||||||||||||||||||||||||||||||||||||||.||.:.|.||.|
Human   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEGEE 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84B	NP_476772.1	PTZ00335	1..439	CDD:185562	402/437 (92%)
TUBA8	NP_061816.1	PTZ00335	1..439	CDD:185562	402/437 (92%)
		MREC motif. /evidence=ECO:0000250|UniProtKB:P68363	1..4		2/2 (100%)