Protein Alignment alphaTub84B and Tubb4a

DIOPT Version :10

• Sequence 1: NP_476772.1
• Gene: alphaTub84B / 40848
• FlyBaseID: FBgn0003884
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_543158.1
• Gene: Tubb4a / 29213
• RGDID: 619730
• Length: 444
• Species: Rattus norvegicus
• Alignment Length: 456
• Identity: 183/456 - (40%)
• Similarity: 272/456 - (59%)
• Gaps: 21/456 - (4%)

  Fly     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDD----SFNTFFSETGAGKH 61
            |||.:.:..||.|.|||...||:...||||.|.|      |..|..|    ..|.:::|...|.:
  Rat     1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTG------TYHGDSDLQLERINVYYNEATGGNY 59

  Fly    62 VPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLA 126
            |||||.|||||..:|.||:|.:.|:|.|:..:.|:..|.||:|:||||.|.|:||.|||.:||.|
  Rat    60 VPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEA 124

  Fly   127 DQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTT 191
            :.|..||||.:.||.|||||||..:||:.::..::..:....|::.|:|:||..||||||:.|:.
  Rat   125 ESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSV 189

  Fly   192 HTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQ 256
            |..:|::|..:.:||||:||||.|.|.:..|||.:||.|:...:|.:|..|||.|.||.||.:..
  Rat   190 HQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 254

  Fly   257 TNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRG 321
            .|:||:||:||.:..:||:.|.....:..|:|.|:|...|:..|.|..||||||:|:....::||
  Rat   255 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 319

  Fly   322 DVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAE 386
            .:..|:|:..:.::::|.:..||:|.|...|..:...||        ..::.|...:.|:|||.|
  Rat   320 RMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPP--------RGLKMAATFIGNSTAIQE 376

  Fly   387 AWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAR---EDLAALEKDYEEVGMDSGDGEGEGAE 448
            .:.|:..:|..|:.::||:|||.||||:|.||:||.   .||.:..:.|::...:.|:.|.|..|
  Rat   377 LFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEE 441

  Fly   449 E 449
            |
  Rat   442 E 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84B	NP_476772.1	PTZ00335	1..439	CDD:185562	178/444 (40%)
Tubb4a	NP_543158.1	PLN00220	1..427	CDD:215107	178/439 (41%)