Protein Alignment alphaTub84B and TUBA1B

DIOPT Version :10

• Sequence 1: NP_476772.1
• Gene: alphaTub84B / 40848
• FlyBaseID: FBgn0003884
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_006073.2
• Gene: TUBA1B / 10376
• HGNCID: 18809
• Length: 451
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 435/451 - (96%)
• Similarity: 445/451 - (98%)
• Gaps: 1/451 - (0%)

  Fly     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRA 65
            |||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||
Human     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRA 65

  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCT 130
            |||||||||:|||||||||||||||||||||||||||||||||||||||:|||||||||||||||
Human    66 VFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCT 130

  Fly   131 GLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTL 195
            ||||||:||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||
Human   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195

  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260
            ||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||
Human   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLV 260

  Fly   261 PYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVP 325
            |||||||||.||||||||||||||||||||||||||||||||||||||||||||||:||||||||
Human   261 PYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVP 325

  Fly   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            ||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||
Human   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEG-EGAEEY 450
            ||||||||||||||||||||||||||||||||||:|||||||||||:||.:||| |..|||
Human   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTub84B	NP_476772.1	PTZ00335	1..439	CDD:185562	426/437 (97%)
TUBA1B	NP_006073.2	PTZ00335	1..440	CDD:185562	427/438 (97%)
		MREC motif. /evidence=ECO:0000269|PubMed:31727855	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		12/18 (67%)