DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tailor and PAP2

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_014526.1	Gene:	PAP2 / 854034	SGDID:	S000005475	Length:	584	Species:	Saccharomyces cerevisiae

Alignment Length:	384	Identity:	79/384 - (20%)
Similarity:	137/384 - (35%)	Gaps:	126/384 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 QEKKQAQVKARQHITVRLPKKARAMIVGEITNVFKDKYPIA-----DKLKVIPEYDVIE-QDLCK 249
            ::.:|.:.:.:|.:.::..|:.      ||.|.   .||..     .|.|.|.::...| :|...
Yeast   133 EQAEQEEEREKQELEIKKEKQK------EILNT---DYPWILNHDHSKQKEISDWLTFEIKDFVA 188

  Fly   250 LLSPG---------------------FPKQPLRVYKFGSRITGIGNRSSDLDLFV--DIG--KSG 289
            .:||.                     :|...|.|  |||..|.:....||:|..|  ::|  :|.
Yeast   189 YISPSREEIEIRNQTISTIREAVKQLWPDADLHV--FGSYSTDLYLPGSDIDCVVTSELGGKESR 251

  Fly   290 NTFHTFEHRASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLNSMGF 354
            |..::.........:|           :|    :..:.:|||||||.....:||..|:     .|
Yeast   252 NNLYSLASHLKKKNLA-----------TE----VEVVAKARVPIIKFVEPHSGIHIDV-----SF 296

  Fly   355 CNTN------LLKYIFESQPLTQYMCIYVKNWLERCKL----TEQISTYSITLMVIYFLQLQALL 409
            ..||      |::...:..|..:.:.:.||.:|...:|    |..:..:||..:|..||.:.
Yeast   297 ERTNGIEAAKLIREWLDDTPGLRELVLIVKQFLHARRLNNVHTGGLGGFSIICLVFSFLHMH--- 358

  Fly   410 PPIAMLQIEDAANQAVLVGPWVVNFAQKSFSELGLQQLKATVPVIKGFLRNFFAYFAK-FDYEHF 473
            |.|...:|:...|..||                               |..||..:.| |.|:..
Yeast   359 PRIITNEIDPKDNLGVL-------------------------------LIEFFELYGKNFGYDDV 392

  Fly   474 LVCPYIGQANVEIAKIERMLHARYSAYVSDNPECSIQ-LKKP--MVVQDPIQLNHNVTK 529
            .    :|.::            .|..|...:...:|| :|.|  :.:|||...::|:::
Yeast   393 A----LGSSD------------GYPVYFPKSTWSAIQPIKNPFSLAIQDPGDESNNISR 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	33/149 (22%)
PAP2	NP_014526.1	TRF4	116..584	CDD:227585	79/384 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810