DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tailor and tent2

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001018436.1	Gene:	tent2 / 553626	ZFINID:	ZDB-GENE-050522-536	Length:	489	Species:	Danio rerio

Alignment Length:	549	Identity:	128/549 - (23%)
Similarity:	211/549 - (38%)	Gaps:	170/549 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 MMPNKLLYMNPLTMEAHFFLQTLNSVNQTTNPPQLDPHLANLLERIMVGIESYLDRNPTYVLPQE 123
            |:|...::.:.....:|.|...|             ||..:..:|    ||::|:....::.| .
Zfish     1 MLPRPYIFSHNDGPSSHLFQHVL-------------PHNVSQQQR----IEAHLNSTNNFIGP-P 47

  Fly   124 MAAPGEGVAFV-----QPQELQTIKRTFSCSSCSNRIVGTTIAKAVAHLSEQHPK------PNPN 177
            |.||    .|:     .|.||..:    :||  .|..:|....:.:...|:.:.|      |:|:
Zfish    48 MNAP----RFIPTYQWTPVELSDV----ACS--PNGPMGNNRKRRIQDNSDINLKRQRFSCPSPH 102

  Fly   178 NQPV-------QPHPTHQTKQEKKQAQVKARQHITVRLPKKARAMIV--------GEI--TNVFK 225
            ||..       ||.....|.:|             |..|..:.|..:        ||.  .|.|.
Zfish   103 NQSARNSNFTSQPVTRPVTGRE-------------VTCPTCSSATFIPGGCVPSLGETCHQNAFS 154

  Fly   226 DKYPIADKL--KVIPEYDVIEQ-----------------DLCKLLSPGFPKQPLRVYKFGSRITG 271
            .. .:.|||  :::..:...||                 |:.|:    ||  ..:|:..||.:.|
Zfish   155 PS-SVKDKLSQQILNLFFACEQQSDDLEKKESCRAALQTDIQKI----FP--CAKVFLGGSSLNG 212

  Fly   272 IGNRSSDLDLFVDIGKSGNTFHTFEHRASNATVAKLRAMRKFFCDSEDWRLINFIE-----QARV 331
            .|:||||.||.:.|.:.     ...||.....|..|  :||....      :::||     :|:|
Zfish   213 FGSRSSDADLCLVIEEG-----PVNHRKDAVYVLSL--VRKLLYK------LSYIEKPQLIRAKV 264

  Fly   332 PIIKTCHLPTGIECDICL-NSMGFCNTNLLK-YIF---ESQPLTQYMCIYVKNWLERCKLTE--- 388
            ||:|.....:|:|.|:.. |::|..||.||: |.|   ..:||.    :.:|.|.....:.:
Zfish   265 PIVKFRDRISGVEFDLNFNNTVGIRNTFLLRTYAFVEKRVRPLV----LVIKKWANHHCINDASR 325

  Fly   389 -QISTYSITLMVIYFLQLQALLPPIAMLQIE-----DAANQAVLV--GPW-VVNFAQKSFSELGL 444
             .:|:|::.|||:::||... .|.|..||.:     |......||  ||. :..|..::.|.||
Zfish   326 GTLSSYTLVLMVLHYLQTLP-EPVIPCLQRDYPTCFDPKMDIHLVPSGPSDIPAFVSRNQSSLG- 388

  Fly   445 QQLKATVPVIKGFLRNFFAYFAKFD-------------------YEHFLVC---PYIGQANVEIA 487
                   .:..|||| ::|...|:|                   ::...:|   |: .:.|...|
Zfish   389 -------DLFLGFLR-YYATVFKWDKQVISVRMARTLPKSNCKEWKDKFICVEEPF-NRTNTARA 444

  Fly   488 KIERM-LHARYSAYVSDNPECSIQLKKPM 515
            ..||| ..|..:|::..:.  .:||:|.:
Zfish   445 VHERMKFEAIKAAFIESHR--LLQLRKDL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551	11/55 (20%)
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	40/142 (28%)
tent2	NP_001018436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	93..118		6/24 (25%)
		NT_PAP_TUTase	182..298	CDD:143392	38/134 (28%)
		PAP_assoc	386..440	CDD:281779	11/63 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586703
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840