Protein Alignment Tailor and MTPAP

DIOPT Version :9

• Sequence 1: NP_001262327.1
• Gene: Tailor / 40847
• FlyBaseID: FBgn0037470
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_060579.3
• Gene: MTPAP / 55149
• HGNCID: 25532
• Length: 582
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 92/408 - (22%)
• Similarity: 177/408 - (43%)
• Gaps: 90/408 - (22%)

  Fly   193 KKQAQVKARQHITVRLPKKARAMIVGEITNVFKDKYPIADKLK-VIPEYDVIEQD------LCKL 250
            |.|...::|...:.:||:..:     ::..:......|.|:|. ::.|:.:.|::      .|.|
Human   154 KNQTSERSRVRSSNQLPRSNK-----QLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSL 213

  Fly   251 L----SPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGK---------SGNTFHTF------- 295
            :    :..||...:|  .|||.:...|....|||:|:|:.:         |||....|
Human   214 IEDMAAAYFPDCIVR--PFGSSVNTFGKLGCDLDMFLDLDETRNLSAHKISGNFLMEFQVKNVPS 276

  Fly   296 EHRASNATVAKLRAMRKFF---CDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLNSMGFCNT 357
            |..|:...::.|......|   |..     :..|..||.|:::..|..:|.:||:..|:.....:
Human   277 ERIATQKILSVLGECLDHFGPGCVG-----VQKILNARCPLVRFSHQASGFQCDLTTNNRIALTS 336

  Fly   358 NLLKYIFES-QPLTQYMCIYVKNWLERCKLTEQ-----ISTYSITLMVIYFLQLQALLPPI---- 412
            :.|.||:.: ....:.:...|:.|.....||..     |:.:|:|:|||:|||.::  |||
Human   337 SELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRS--PPILPTL 399

  Fly   413 -AMLQIEDAANQAVLVG---PWVVNFAQKSFSELGLQQLKATVPVIKGFLRNFFAYFAKFDYEHF 473
             ::..:.||.::.|:.|   .:|     :..|.:...|...|:.::   |:.||.||..|.::.
Human   400 DSLKTLADAEDKCVIEGNNCTFV-----RDLSRIKPSQNTETLELL---LKEFFEYFGNFAFDK- 455

  Fly   474 LVCPYIGQANVEIAKIERMLHARYSAYVSDNPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQT 538
                  ...|:...:.:            :.|:.|     |:.:|:|.:.:.|::|.|::..||.
Human   456 ------NSINIRQGREQ------------NKPDSS-----PLYIQNPFETSLNISKNVSQSQLQK 497

  Fly   539 FVDYCQQTAELLEEPSTN 556
            |||..:::|.:|::..|:
Human   498 FVDLARESAWILQQEDTD 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
		NT_PAP_TUTase	245..364	CDD:143392	34/147 (23%)
MTPAP	NP_060579.3	NT_PAP_TUTase	206..344	CDD:143392	35/144 (24%)
		PAP_assoc	440..483	CDD:281779	12/69 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1188122at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.880