DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tailor and Gld2

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001262829.1	Gene:	Gld2 / 42602	FlyBaseID:	FBgn0038934	Length:	1364	Species:	Drosophila melanogaster

Alignment Length:	465	Identity:	98/465 - (21%)
Similarity:	170/465 - (36%)	Gaps:	135/465 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 QPQELQTIKRTFSCS---SCSNRIVGTTIAKAVAHLSEQHPKPNPNNQPVQPHPTHQ-------- 188
            ||..: ::....|||   |.|..::....:|:...:.|::     |:....|...|.
  Fly   846 QPDNI-SVASNLSCSPSASSSKSVLAPMASKSNITMPEEN-----NDDDELPLVVHNRYWREFFG 904

  Fly   189 -TKQEKKQAQVKARQHITVRLPKKARAMIVG--------------------EITNVFKDK----- 227
             |..::...:.|   .:.:|.|.|    ::|                    :..:|:|.|
  Fly   905 YTPADRFLLRAK---FVEMRRPPK----VMGCKNKWDPLSLSVWKKFLESQQTRHVYKIKMRLWR 962

  Fly   228 --YPIADKLKVIPEYDVIEQDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGKSGN 290
              |.:|  :|..|.|.                    :|..||.|:..|::.||:|:.:....:.|
  Fly   963 AIYTVA--MKNYPRYG--------------------LYLVGSSISYFGSKCSDMDICMLACTNPN 1005

  Fly   291 TFHTFEHRASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIK---TCHLPTGIECDICL-NS 351
            .....|      .|..|..|::....:..::..|.|| |||||::   .||   .:|.||.. ||
  Fly  1006 IDSRME------AVYHLHVMKELLGRTNMFQDFNLIE-ARVPILRFTDRCH---KVEVDINFNNS 1060

  Fly   352 MGFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTE----QISTYSITLMVIYFLQLQALLPPI 412
            :|..||:||....:.....:.|.:.||.|.:...:..    .||:||:.||||:|||:.| .||:
  Fly  1061 VGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNAKNMTISSYSLMLMVIHFLQVGA-SPPV 1124

  Fly   413 ------------AMLQIEDAANQAVLVGPWVVNFAQKSFSELGLQQLKATVPVIKGFLRNFFAYF 465
                        .:||..|              |.....:|:...........:...|.:|..|:
  Fly  1125 LPCLHNLYPEKFGLLQPND--------------FGYVDMNEVMAPYQSDNSQTLGDLLLSFLHYY 1175

  Fly   466 AKFDYEHFLVCPYIGQA-NVEIAKIERMLHARYSAYVSDNPECSIQLKKPMVVQDPIQLNHNVTK 529
            :.|||..:.:...:|.. .:|:.:            .:..|:..|.....:.:::|.. ..|..:
  Fly  1176 SVFDYGKYAISIRVGGVLPIEVCR------------AATAPKNDIHQWNELCIEEPFD-QTNTAR 1227

  Fly   530 AVTKYGLQTF 539
            :|  |...||
  Fly  1228 SV--YDTDTF 1235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	33/122 (27%)
Gld2	NP_001262829.1	NT_PAP_TUTase	954..1073	CDD:143392	40/150 (27%)
Gld2	NP_001262829.1	PAP_assoc	1163..1224	CDD:281779	11/73 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840