DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tailor and wisp

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001285144.1	Gene:	wisp / 32152	FlyBaseID:	FBgn0260780	Length:	1373	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	107/446 - (23%)
Similarity:	177/446 - (39%)	Gaps:	110/446 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 VAH-LSEQHP------KPN------------PNNQPVQPHPTHQTKQEKKQAQ------------ 197
            |.| |.:|||      :|:            |:..|..|||:..:......|.
  Fly   878 VQHPLHQQHPPSHASHRPHGQMGGHAMSSYVPHRPPPPPHPSISSPNPTPVATGAGGPWYEMILP 942

  Fly   198 -----VKARQ-HITVRLPKKARAM-----IVGEITNVFKDKYPIADKLKVIPEYDVIEQDLCKLL 251
                 .:||. .:||: |:|...|     :..||...|:......:|.|       ::..|.:.|
  Fly   943 PDRYLAQARNIEVTVQ-PEKLICMCKYDNLSAEIWKRFRGAQQTHNKFK-------LKMRLWRYL 999

  Fly   252 -----SPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGKSG--------NTFHTFEHRASNAT 303
                 .|.|.:  .|:...||.|||.|..|||:|:.: :.:.|        :..|.|.:......
  Fly  1000 YLWMHQPMFER--YRICLVGSTITGFGTDSSDIDMCL-LPEQGVHPHQHQYHQHHHFHNEKRTEA 1061

  Fly   304 VAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLNS-MGFCNTNLLKYIFESQ 367
            :..|........|:|.::..|.|| |||||::...:..|||.|:..|: :|..||.||:...:..
  Fly  1062 LIILTLFNAVLKDTEVFQDFNLIE-ARVPILRFKDISNGIEVDLNFNNCVGIKNTYLLQLYAQMD 1125

  Fly   368 PLTQYMCIYVKNWLERCKLTE----QISTYSITLMVIYFLQ----------LQALLPPIAMLQIE 418
            ..|:.:.:.||.|.:...:.:    .||:||:.|||:::||          |.:|.|....|..:
  Fly  1126 WRTRPLVVIVKLWAQYHDINDAKRMTISSYSLVLMVLHYLQHACVPHVLPCLHSLYPEKFQLGQQ 1190

  Fly   419 DAANQAVLVGPWVVNFAQKSFSELGLQQLKATVPVIKGFLRNFFAYFAKFDYEHFLVCPYIGQAN 483
            |..: ..|:.|      .:.:..|..|.|..       .|..||.|::.||:.:|.:.  |....
  Fly  1191 DCLD-LDLIEP------IEPYQALNTQTLGE-------HLLGFFKYYSTFDFRNFAIS--IRTGG 1239

  Fly   484 VEIAKIERMLHARYSAYVSDNPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGLQTF 539
            |......||         :.:|:..:...|.:.:::|..|: |..::|  |...||
  Fly  1240 VLPVSTCRM---------AKSPKNDVYQWKELNIEEPFDLS-NTARSV--YDGPTF 1283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	39/132 (30%)
wisp	NP_001285144.1	NT_PAP_TUTase	987..1122	CDD:143392	41/145 (28%)
wisp	NP_001285144.1	PAP_assoc	1211..1272	CDD:281779	16/79 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840