DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tailor and Tut4

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_038965897.1	Gene:	Tut4 / 313481	RGDID:	1310138	Length:	1652	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	84/329 - (25%)
Similarity:	140/329 - (42%)	Gaps:	83/329 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 EYDVIEQDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGKSGNTFHTFE-HRASNA 302
            |||                :..|:..|||...|.|.|.||||:.:          |.| |..:..
  Rat  1005 EYD----------------EKARLCLFGSSKNGFGFRDSDLDICM----------TLEGHENAEK 1043

  Fly   303 TVAK--LRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICL-NSMGFCNTNLLKYIF 364
            ...|  :..:.|........|.|..|..|:|||:|..|..:|:|.||.| |::...||.:|....
  Rat  1044 LNCKEIIENLAKILKRHPGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYA 1108

  Fly   365 ESQPLTQYMCIYVKNWLERCKLTE----QISTYSITLMVIYFLQLQALLPPIAMLQ-IEDAAN-- 422
            ...|..||:...:|.:.:||.:.:    .:|:|:..|||:|||| |...|.|.:|| |.|...
  Rat  1109 AIDPRVQYLGYTMKVFAKRCDIGDASRGSLSSYAYILMVLYFLQ-QRKPPVIPVLQEIFDGKQIP 1172

  Fly   423 QAVLVGPWVVNFAQKSFSELGLQQLKATVPVI-----------KGFLRNFFAYFAKFDYEHFLVC 476
            |.::.| |...|..|:      ::||..:|.:           .|.||   .|..:||::.:::
  Rat  1173 QRMVDG-WNAFFFDKT------EELKKRLPSLGKNTESLGELWLGLLR---FYTEEFDFKEYVI- 1226

  Fly   477 PYIGQANVEIAKIERMLHARYSAYVSDNPECSIQLKKPMVVQDPIQLNHN----VTKAVTKYGLQ 537
                  ::...|:......::::             |.:.::||..||||    |::.:|.:.::
  Rat  1227 ------SIRQKKLLTTFEKQWTS-------------KCIAIEDPFDLNHNLGAGVSRKMTNFIMK 1272

  Fly   538 TFVD 541
            .|::
  Rat  1273 AFIN 1276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	34/122 (28%)
Tut4	XP_038965897.1	TUTase	287..618	CDD:408858
		PAP_assoc	650..699	CDD:397761
		TRF4	948..>1280	CDD:227585	84/329 (26%)
		NT_PAP_TUTase	990..1108	CDD:143392	37/128 (29%)
		AIR1	<1295..>1384	CDD:227414
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910