DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tailor and Tent4b

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_006255323.1	Gene:	Tent4b / 307745	RGDID:	1309587	Length:	700	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	91/382 - (23%)
Similarity:	140/382 - (36%)	Gaps:	111/382 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 KKARAMIVGEITNVFKDKYPIADKLKVIPEYDVIEQDLCKLLSPGFPKQPLRVYKFGSRITGIGN 274
            :|.|..:|..|.:|.|:.:|.||                             |..|||..||:..
  Rat   219 EKMRMEVVSRIESVIKELWPSAD-----------------------------VQIFGSFKTGLYL 254

  Fly   275 RSSDLDLFVDIGKSGN-TFHTFEHRASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCH 338
            .:||:||.| .||..| ...|.|           .|:||.....||  .:..:::|.|||||...
  Rat   255 PTSDIDLVV-FGKWENLPLWTLE-----------EALRKHKVADED--SVKVLDKATVPIIKLTD 305

  Fly   339 LPTGIECDICLN-SMGFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTE----QISTYSITLM 398
            ..|.::.||..| ..|....:|:|...:..|:..|:.:.:|.:|.:..|.|    .|.:||:.||
  Rat   306 SFTEVKVDISFNVQNGVRAADLIKDFTKKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSYSLFLM 370

  Fly   399 VIYFLQLQALLPPIAMLQIEDAANQAVLVGPWVVNFAQKSFSELG--LQQLKATVPVIKGFLRNF 461
            .:.||||...         |||.......|..::.|    |...|  ...||..:.:..|
  Rat   371 AVSFLQLHPR---------EDACIPNTNYGVLLIEF----FELYGRHFNYLKTGIRIKDG----- 417

  Fly   462 FAYFAKFDYEHFLVCPY----------------IGQANVEIAKIERMLHARY---SAYVSDNPEC 507
            .:|.||.:.:..::..|                :|:::....::::.....|   |..||...:|
  Rat   418 GSYVAKDEVQKNMLDGYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAFDYAYVVLSHAVSPIAKC 482

  Fly   508 SIQLKKPMVVQDPIQLNHNVTKAVTKY--------GLQTFVDYCQQTAELLEEPSTN 556
            ....:...::...|:    ||..||.|        |||.           ..|||.|
  Rat   483 YPNNETESILGRIIR----VTDEVTTYRDWISKQWGLQN-----------RPEPSCN 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	34/120 (28%)
Tent4b	XP_006255323.1	NT_PAP_TUTase	221..331	CDD:143392	42/152 (28%)
Tent4b	XP_006255323.1	PAP_assoc	389..449	CDD:281779	11/68 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810