DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tailor and Tent4a

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_006227844.2	Gene:	Tent4a / 306672	RGDID:	1307356	Length:	784	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	107/456 - (23%)
Similarity:	165/456 - (36%)	Gaps:	146/456 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 SCSSCSNRIVGT--------TIAKAVAHLSEQHP---KPNPNNQPVQPHPTHQTKQEKKQAQVKA 200
            |.||.|:..:|.        :.|...||   .||   .|.|...|    |.||....:::.:.||
  Rat   129 SSSSSSSTSLGRAGSGRTFFSFADGAAH---AHPGPRGPTPAGSP----PQHQFHPGRRKRENKA 186

  Fly   201 ------------------------RQHITVRLPKKARAMIVG------EITNVFKDKYP----IA 231
                                    .|......|.|:||...|      ||.:.:....|    .|
  Rat   187 STYGLNYLLSGSRAATLSGGGGPGAQAARPGTPWKSRAYSPGIQGLHEEIIDFYNFMSPCPEEAA 251

  Fly   232 DKLKVIPEYDVIEQDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGK-SGNTFHTF 295
            .:.:|:...:.:.:||       :|...:::  |||..||:...:||:||.| .|| ........
  Rat   252 MRREVVKRIETVVKDL-------WPSADVQI--FGSFSTGLYLPTSDIDLVV-FGKWERPPLQLL 306

  Fly   296 EHRASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLN-SMGFCNTNL 359
            |.......||:.       |.      |..:::|.|||||.....|.::.||..| ..|......
  Rat   307 EQALRKHNVAEP-------CS------IKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEF 358

  Fly   360 LKYIFESQPLTQYMCIYVKNWLERCKLTE----QISTYSITLMVIYFLQLQALLPPIAMLQIEDA 420
            :|...:...|..|:.:.:|.:|.:..|.|    .||:||:.||.|.||||.   |.|      ||
  Rat   359 IKNYMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLH---PRI------DA 414

  Fly   421 ANQAVLVGPWVVNFAQ---KSFSELGLQQLKATVPVIKGFLRNFFAYFAKFDYEHFLVCPYIGQA 482
            ......:|..:|.|.:   ::|:     .||..:.:.:|     .||.||
  Rat   415 RRADENLGMLLVEFFELYGRNFN-----YLKTGIRIKEG-----GAYIAK--------------- 454

  Fly   483 NVEIAKIERMLHARYSAYVSDNPECSIQLKKP--MVVQDPIQLNHNVTKAVTKYGL----QTFVD 541
                   |.::.|..|.|            :|  :.::||:...::|.:  :.||.    |.| |
  Rat   455 -------EEIMKAMTSGY------------RPSMLCIEDPLLPGNDVGR--SSYGAMQVKQVF-D 497

  Fly   542 Y 542
            |
  Rat   498 Y 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	32/120 (27%)
Tent4a	XP_006227844.2	TRF4	232..>537	CDD:227585	83/346 (24%)
Tent4a	XP_006227844.2	KLF8_12_N	<620..>719	CDD:424081
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810