DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tailor and cid1

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_594901.1	Gene:	cid1 / 2542420	PomBaseID:	SPAC19D5.03	Length:	405	Species:	Schizosaccharomyces pombe

Alignment Length:	390	Identity:	90/390 - (23%)
Similarity:	161/390 - (41%)	Gaps:	103/390 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 EKKQAQVKARQHIT-----VRLPKKARAM------IVGEI---TNVFKDKYPIADKLKVIPEYDV 242
            |:.:|::....||:     .::|...:..      :..||   ...||:|....|.|:
pombe    16 EEIEAEIHKNLHISKSCSYQKVPNSHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLR------- 73

  Fly   243 IEQDLC-KLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGKSGNTFHTFEHRASNATVAK 306
                || |.:||     ...:..|||..:|:..::||:||.|          ..:.|..:.|:|
pombe    74 ----LCLKRISP-----DAELVAFGSLESGLALKNSDMDLCV----------LMDSRVQSDTIA- 118

  Fly   307 LRAMRKFFCDSEDWRLINFIEQARVPIIK-TCHLPTG----IECDICLNS-MGFCNTNLLKYIFE 365
            |:...:...:..:.:   |:::||:|||| |.....|    .:|||..|: :...||.||....:
pombe   119 LQFYEELIAEGFEGK---FLQRARIPIIKLTSDTKNGFGASFQCDIGFNNRLAIHNTLLLSSYTK 180

  Fly   366 SQPLTQYMCIYVKNWLERCKLTE----QISTYSITLMVIYFLQLQALLPPIAMLQIEDAANQAVL 426
            .....:.|.:.||:|.:|.::..    .:|:|...|||:|:| :..:.||:....:.....|..:
pombe   181 LDARLKPMVLLVKHWAKRKQINSPYFGTLSSYGYVLMVLYYL-IHVIKPPVFPNLLLSPLKQEKI 244

  Fly   427 VGPWVVNFAQK--------SFSELGLQQLKATVPVIKGFLRNFFAYFAKFDYEHFLVC-----PY 478
            |..:.|.|..|        ::|.||        .::.||.| |:||  ||:....:|.     .|
pombe   245 VDGFDVGFDDKLEDIPPSQNYSSLG--------SLLHGFFR-FYAY--KFEPREKVVTFRRPDGY 298

  Fly   479 IGQ-------ANVEIAKIERMLHARYSAYVSDNPECSIQLKKPMVVQDPIQLNHNVTKAVTKYGL 536
            :.:       |.......::::..||.                :.::||.:::|||.:.|:..||
pombe   299 LTKQEKGWTSATEHTGSADQIIKDRYI----------------LAIEDPFEISHNVGRTVSSSGL 347

Fly 537 536
pombe 348 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	35/125 (28%)
cid1	NP_594901.1	TRF4	1..405	CDD:227585	90/390 (23%)
		NT_PAP_TUTase	65..178	CDD:143392	38/142 (27%)
		PAP_assoc	267..336	CDD:281779	17/95 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12271
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870