DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tailor and Tent4a

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_006517250.1	Gene:	Tent4a / 210106	MGIID:	2682295	Length:	732	Species:	Mus musculus

Alignment Length:	453	Identity:	106/453 - (23%)
Similarity:	165/453 - (36%)	Gaps:	140/453 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 SCSSCSNRIVGT--------TIAKAVAHLSEQHPKPNPNNQPVQPHPTHQTKQEKKQAQVKA--- 200
            |.||.|:..:|.        :.|...||   .||.|. .:.|....|.||....:::.:.||
Mouse   130 SSSSSSSTSLGRAGSGRTFFSFADGAAH---AHPGPR-GSTPAGSPPQHQFHPGRRKRENKASTY 190

  Fly   201 ---------------------RQHITVRLPKKARAMIVG------EITNVFKDKYP----IADKL 234
                                 .|......|.|:||...|      ||.:.:....|    .|.:.
Mouse   191 GLNYLLSGSRAATLSGGGGPGAQAARPGTPWKSRAYSPGIQGLHEEIIDFYNFMSPCPEEAAMRR 255

  Fly   235 KVIPEYDVIEQDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDLFVDIGK-SGNTFHTFEHR 298
            :|:...:.:.:||       :|...:::  |||..||:...:||:||.| .|| ........|..
Mouse   256 EVVKRIETVVKDL-------WPTADVQI--FGSFSTGLYLPTSDIDLVV-FGKWERPPLQLLEQA 310

  Fly   299 ASNATVAKLRAMRKFFCDSEDWRLINFIEQARVPIIKTCHLPTGIECDICLN-SMGFCNTNLLKY 362
            .....||:.       |.      |..:::|.|||||.....|.::.||..| ..|......:|.
Mouse   311 LRKHNVAEP-------CS------IKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKN 362

  Fly   363 IFESQPLTQYMCIYVKNWLERCKLTE----QISTYSITLMVIYFLQLQALLPPIAMLQIEDAANQ 423
            ..:...|..|:.:.:|.:|.:..|.|    .||:||:.||.|.||||.   |.|      ||...
Mouse   363 YMKKYSLLPYLILVLKQFLLQRDLNEVFTGGISSYSLILMAISFLQLH---PRI------DARRA 418

  Fly   424 AVLVGPWVVNFAQ---KSFSELGLQQLKATVPVIKGFLRNFFAYFAKFDYEHFLVCPYIGQANVE 485
            ...:|..:|.|.:   ::|:     .||..:.:.:|     .||.||
Mouse   419 DENLGMLLVEFFELYGRNFN-----YLKTGIRIKEG-----GAYIAK------------------ 455

  Fly   486 IAKIERMLHARYSAYVSDNPECSIQLKKP--MVVQDPIQLNHNVTKAVTKYGL----QTFVDY 542
                |.::.|..|.|            :|  :.::||:...::|.:  :.||.    |.| ||
Mouse   456 ----EEIMKAMTSGY------------RPSMLCIEDPLLPGNDVGR--SSYGAMQVKQVF-DY 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	32/120 (27%)
Tent4a	XP_006517250.1	TRF4	233..>538	CDD:227585	83/346 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810