DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tailor and F43H9.3

DIOPT Version :9

Sequence 1:	NP_001262327.1	Gene:	Tailor / 40847	FlyBaseID:	FBgn0037470	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_505067.1	Gene:	F43H9.3 / 179181	WormBaseID:	WBGene00018399	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	429	Identity:	89/429 - (20%)
Similarity:	157/429 - (36%)	Gaps:	113/429 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 QTIKRTFSCSSCSNRIVGTTIAKAVAHLSEQHPKPNPNNQPVQPHPTHQTKQEKKQAQVKARQHI 204
            :.::::|:.|.|            ::|       |:.:|:.|:|           .:.:....:|
Worm    11 RVLQQSFASSEC------------ISH-------PSSSNENVKP-----------ISNLPYVDYI 45

  Fly   205 TVRLPKKARAM--IVGEITNVFKDKYPIADKLKVIPEYDVIEQDLCKLLSPGFPKQPLRVYKFGS 267
            ..:.|:|...|  .|.|:.:..|:    ....||:.    ..:||..|:   ..|..:.:...||
Worm    46 KKKYPEKLEKMNEQVAELNSQRKE----CKNTKVLS----FIKDLNSLI---LNKNAVELIPVGS 99

  Fly   268 RITGIGNRSSDLDLFVDIGKSGNTFHTFEHRASNATVAKLRAMRKF--FCDSEDWRLINFIE--- 327
            .:|...|:.||.| ||...|..:..|.|..........|...|..|  ..:.|..:|...:|
Worm   100 MVTNFVNKQSDFD-FVFFPKRDDQRHRFLRDFHQNPSFKQNFMSVFAKLIERESAKLGEPVEKIV 163

  Fly   328 ---QARVPIIKTCHLPTGIECDICL---NSMGFCNTNLLKYIFESQPLTQYMCIYVKNWLER-CK 385
               :.|||:|...:: :|:..|:..   |.....||:|:|    ...|..:....:..||.. |.
Worm   164 ELPRMRVPLIIVRYI-SGLSIDVQFPEENYHAIRNTHLMK----MYKLCDHRFTLLFLWLRAICD 223

  Fly   386 LTE-------QISTYSITLMVIYFLQLQALLPPIAML---------------QIEDAANQAVLVG 428
            ..|       .:|:|.:.|:|::|||.:..|.|..:|               .|...|.......
Worm   224 KLEVRNSKYGLLSSYHLLLLVVHFLQSEQALSPWPVLPVLAKTHPNLVTSEIPISKVAELIKSEN 288

  Fly   429 PWVVNFAQKSFSELGLQQLKATVPVIKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERML 493
            |.:.:|:..|.:::.:.:|     :|:     |..|     |.||       .|..|...||:.|
Worm   289 PCLSDFSWTSHNKMAISEL-----IIR-----FVDY-----YNHF-------NAAKEAIYIEKGL 331

  Fly   494 HARYSAYVSDNPECSIQLKKPMVVQDPIQL--NHNVTKA 530
            ..:......   |..:||..|   ..|:.:  :|:.:.|
Worm   332 ALKRKQVFG---EVRLQLIDP---YSPVSVCRSHHASSA 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551
Tailor	NP_001262327.1	NT_PAP_TUTase	245..364	CDD:143392	33/129 (26%)
F43H9.3	NP_505067.1	NT_Pol-beta-like	79..204	CDD:386233	33/133 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810