Protein Alignment Tailor and gldr-2

DIOPT Version :9

• Sequence 1: NP_001262327.1
• Gene: Tailor / 40847
• FlyBaseID: FBgn0037470
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001021434.1
• Gene: gldr-2 / 173373
• WormBaseID: WBGene00009284
• Length: 808
• Species: Caenorhabditis elegans
• Alignment Length: 652
• Identity: 132/652 - (20%)
• Similarity: 237/652 - (36%)
• Gaps: 195/652 - (29%)

  Fly    12 KKAMFSNAERQ--YFETVRPRKT--------------------SLPGSTAPN----IAAPVTKAT 50
            ||.:.:|.:..  .:.||.|:||                    ..|||::.:    :....::|:
 Worm   160 KKRVLTNLKNAGVGYTTVTPKKTLKNDDDDVEEDVPNETVDPSDAPGSSSSDDIVIVREVASEAS 224

  Fly    51 KKNKTMAEMMPNKLLYMNPLTM-----------------------------------EAHFFLQT 80
            .|.:.|.||...|...:...||                                   |::.|:|.
 Worm   225 PKLRKMREMDGAKKKLIEEATMRLGENRRSPSLDSDTYFGECQQLLHGPTEVYCARPESNQFVQQ 289

  Fly    81 LNSVNQTTNPPQLDPHLANLLERIMVGIESYLDRNPTYVL----------PQEMAAPGEGVAFV- 134
            ....|.|......|.. |..::|..|.||.  |.:...||          .::::...:.:..:
 Worm   290 YEEANSTEASEDEDKE-AVPMKRARVDIEE--DDDDVIVLNMTTSSGVSDKKDVSGSEDEIGDIV 351

  Fly   135 ----------QPQELQTIK----RTFSCSSCSNRI--VGTTIAKAVAHLSEQHPKPNPN-NQPVQ 182
                      :..||:.::    :........|.:  |.:|:      :|.:.|..:.: |:...
 Worm   352 DEWDANDEEEKTDELEELEDDDIQIIEAGDQGNGVEEVSSTV------ISVETPNSSSDENKIYN 410

  Fly   183 PHPTHQTKQEKKQAQV--KARQHITVRLPKKARAMIVGEITNVFKDKYPIADKLKVI-------- 237
            .|.|||..:|.:|..|  :||. |.|.|.::....:...:.::.|..:....:|..:
 Worm   411 GHQTHQIFREVRQLPVNYQART-IGVVLNERIAGSVEKFVNSITKKSFNSVKQLSKLAWDHYLGN 474

  Fly   238 --PEYDVIE-----QDLCKLLSPGFPKQPLRVYKFGSRITGIGNRSSDLDL---FVDIGKSGNTF 292
              |::..::     |.|...:...||...:::...||.:.|.|:.:||:||   |...|..|...
 Worm   475 AQPDFVFLKKMEARQKLFSEIKKLFPDTEIKLQTTGSTVNGCGSFNSDMDLCLCFPTNGYKGQVC 539

  Fly   293 HTFEHRASNATVAKLRAMRKFFCDSEDW-----RLINFIE--QARVPIIKTCHLP--TGIECDIC 348
            ..| |...|.:...||.:.|.|..|. |     ::|..::  .|:|||:|.....  .|||.||.
 Worm   540 DDF-HCDRNYSTKILRKIDKAFRRSH-WSHPLKKIIKTMQLVPAKVPIVKMILNGEFDGIEVDIN 602

  Fly   349 LNSM-GFCNTNLLKYIFESQPLTQYMCIYVKNWLERCKLTEQ----ISTYSITLMVIYFLQ---- 404
            :|:: |..|::|:.|...:......:.:.||:|.....:...    :::|:..|:|:::||
 Worm   603 VNNIAGIYNSHLIHYYSLTDARLPALALLVKHWAMVTGINNAQDGFLNSYTTILLVVHYLQCGVT 667

  Fly   405 ------LQALLP-------PI-AMLQIEDAANQAVLVGP--WVVNFAQKSFSELGLQQLKATVPV 453
                  ||.|.|       |: .:|...|.|::.....|  |       |..||
 Worm   668 PAVIPNLQYLFPHKFDRKLPLNELLLFGDIADKLPTSPPNTW-------SLGEL----------- 714

  Fly   454 IKGFLRNFFAYFAKFDYEHFLVCPYIGQANVEIAKIERMLHARYSAYVSDNPECSIQLKKPMVVQ 518
                |..||.|:.:||:.:|......||. :....:.|.|                 :..|:||:
 Worm   715 ----LIGFFQYYNEFDFTNFGFSIRSGQV-IPRENLPRDL-----------------INSPIVVE 757

  Fly   519 DP 520
            :|
 Worm   758 EP 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tailor	NP_001262327.1	DUF1439	<70..126	CDD:297551	16/100 (16%)
		NT_PAP_TUTase	245..364	CDD:143392	40/131 (31%)
gldr-2	NP_001021434.1	TRF4	483..>799	CDD:227585	76/319 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162424
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840