DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dpck and DCAKD

DIOPT Version :9

Sequence 1:	NP_649692.2	Gene:	Dpck / 40846	FlyBaseID:	FBgn0037469	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001122103.1	Gene:	DCAKD / 79877	HGNCID:	26238	Length:	231	Species:	Homo sapiens

Alignment Length:	223	Identity:	88/223 - (39%)
Similarity:	137/223 - (61%)	Gaps:	0/223 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFIVAVTGGIATGKSTISKVFERQGIPVIDADKIAREIVEPGQPCWRQIREVFGDEVLLPSKEIN 65
            ||:|.:|||||:|||::.:||::.|..|||.|.:||.:|:||.|..|:|.||||.||||.:.:||
Human     1 MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEVLLENGDIN 65

  Fly    66 RAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCKLLVTGHAWIVLDLPLLFETGVLMDFIHKI 130
            |.|||.:||...:.|..||.||||.|.:::..:..|..:.|:.:::||:||||||..|:.::...
Human    66 RKVLGDLIFNQPDRRQLLNAITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHT 130

  Fly   131 VCVTCDSDKQLERLIARNELSESEARHRVDSQMPLDKKCEKSHFVIDNNGSVEEAESSAMSIYNL 195
            |.|.||.|.||.||:.||.|:..:|..|:::|:||..|...:..|:||:|.....:...:.::..
Human   131 VVVYCDRDTQLARLMRRNSLNRKDAEARINAQLPLTDKARMARHVLDNSGEWSVTKRQVILLHTE 195

  Fly   196 MRDSKQHWLNRISFLGLFLIVGFTIYML 223
            :..|.::...|...|.....:...:|:|
Human   196 LERSLEYLPLRFGVLTGLAAIASLLYLL 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dpck	NP_649692.2	DPCK	3..184	CDD:238980	81/180 (45%)
DCAKD	NP_001122103.1	coaE	1..196	CDD:234620	83/194 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153164
Domainoid	1	1.000	166	1.000	Domainoid score	I3903
eggNOG	1	0.900	-	-		E1_COG0237
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5652
Inparanoid	1	1.050	174	1.000	Inparanoid score	I4076
Isobase	1	0.950	-	0	Normalized mean entropy	S1197
OMA	1	1.010	-	-		QHG62494
OrthoDB	1	1.010	-	-		D1263008at2759
OrthoFinder	1	1.000	-	-		FOG0003608
OrthoInspector	1	1.000	-	-		oto90230
orthoMCL	1	0.900	-	-		OOG6_101308
Panther	1	1.100	-	-	LDO	PTHR10695
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1907
SonicParanoid	1	1.000	-	-		X2483
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750