DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dpck and Coasy

DIOPT Version :9

Sequence 1:	NP_649692.2	Gene:	Dpck / 40846	FlyBaseID:	FBgn0037469	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001292911.1	Gene:	Coasy / 71743	MGIID:	1918993	Length:	563	Species:	Mus musculus

Alignment Length:	235	Identity:	56/235 - (23%)
Similarity:	106/235 - (45%)	Gaps:	31/235 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFIVAVTGGIATGKSTISKVFERQGIPVIDADKIAREIVEPGQPCWRQIREVFGDEVLLPSKEIN 65
            ::::.:||...:|||::::..:..|..:||:|.:......||.|.::.:.|.||.::|.....||
Mouse   357 LYVLGLTGISGSGKSSVAQRLKNLGAYIIDSDHLGHRAYAPGGPAYQPVVEAFGTDILHKDGTIN 421

  Fly    66 RAVLGKMIFEDKELRGKLNKITHPTIHRKIFWQVCKLLVTGHAWIVLDLPLLFETGVLMDFIHKI 130
            |.|||..:|.:|:....|..|..|.|.:....::...:..|....|:|..:|.|.| ....:|::
Mouse   422 RKVLGSRVFGNKKQMKILTDIVWPVIAKLAREEMDVAVAKGKTLCVIDAAMLLEAG-WQSMVHEV 485

  Fly   131 VCVTCDSDKQLERLIARNELSESEARHRVDSQMPLDKKCEKSHFVIDNNGSVEEAESSAMSIYNL 195
            ..|.....:.:.|::.|:.|||:.|:.|:.|||...:..|:|:.|:.........:|.....:||
Mouse   486 WTVVIPETEAVRRIVERDGLSEAAAQSRLQSQMSGQQLVEQSNVVLSTLWESHVTQSQVEKAWNL 550

  Fly   196 MRDSKQHWLNRISFLGLFLIVGFTIYMLLKVFNRLPESWQ 235
            ::                              .|||:::|
Mouse   551 LQ------------------------------KRLPKAYQ 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dpck	NP_649692.2	DPCK	3..184	CDD:238980	49/180 (27%)
Coasy	NP_001292911.1	Phosphopantetheine adenylyltransferase	179..357		56/235 (24%)
		PPAT_CoAS	192..338	CDD:173915
		CoaE	358..557	CDD:223315	54/229 (24%)
		DPCK	359..535	CDD:238980	49/176 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910