Protein Alignment CG1105 and Arrdc4

DIOPT Version :10

• Sequence 1: NP_649688.1
• Gene: CG1105 / 40841
• FlyBaseID: FBgn0037465
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001036057.1
• Gene: Arrdc4 / 66412
• MGIID: 1913662
• Length: 415
• Species: Mus musculus
• Alignment Length: 429
• Identity: 113/429 - (26%)
• Similarity: 185/429 - (43%)
• Gaps: 77/429 - (17%)

  Fly     4 KGCELQLDNPWNTYYAGQTVNGQVKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTSEG----K 64
            |||          |.:|:||.|.|......|..:||:.:...|.|.:.|..........|    .
Mouse    26 KGC----------YSSGETVAGHVLLEAAEPVALRGLRLEAQGRATSAWGPSAGARVCIGGGSPA 80

  Fly    65 TENEVTQLKGHEEYFKIQYYLL-GGKNSSETELPPGTHTYPFTCALPPN-LPSSFEGEFGHVRYT 127
            ..:||       ||..::..|| .......|.|.||.|.:||...||.. |.:||.|::|.::|.
Mouse    81 ASSEV-------EYLNLRLSLLEAPAGEGVTLLQPGKHEFPFRFQLPSEPLATSFTGKYGSIQYC 138

  Fly   128 IKVTLDRPWKFDQDMKMAFTVIAPVDLNLNPRVKEPFKLELEKSFCCFCCRSGPLAVITNIPQTG 192
            ::..|:||...||.::....|::.||:|..|.:....|.: ||...|:...|||:::...|.:.|
Mouse   139 VRAVLERPQVPDQSVRRELQVVSHVDVNTPPLLTPMLKTQ-EKMVGCWLFTSGPVSLSVKIERKG 202

  Fly   193 FVSGQVLPITCEVDNTSNVNLTAVKFELRKLVTFHTNQPRSEKRESKV--IIANLSVGPVNGGES 255
            :.:|:.:||..|::|.|:      :..:.|...|.|....:..:...|  ::||:....:..|.:
Mouse   203 YCNGEAIPIYAEIENCSS------RLVVPKAAIFQTQTYLASGKTKTVRHMVANVRGNHIGSGST 261

  Fly   256 RTFTQQM-EIPALPPTNLLNCGIIALDYDLHVECEVSGPHRNLTGKVPITLGTIPLAGVRPPTQF 319
            .|:..:| :||.:.| ::|:|.||.:||.|.|...:.|..| |..::|:.:||||.:|      |
Mouse   262 DTWNGKMLKIPPVTP-SILDCCIIRVDYSLAVYIHIPGAKR-LMLELPLVIGTIPYSG------F 318

  Fly   320 TDAPSAVQSEDPS----LAPTQPVSPASPPGGDGVGGALGWNVADSTGGGSLYPNIPP-PQ---- 375
            ....|:|.|:...    ||...|..|.:||           |.||.........::|| ||
Mouse   319 GRRNSSVASQFSMDMCWLALALPEQPEAPP-----------NYADVVSEEEFSRHVPPYPQPSDC 372

  Fly   376 -----------FVETQYRAPTIAGR-----DDSEHTQMI 398
                       ..|.:::.|.:...     .|::.||.:
Mouse   373 DGEACYSMFACIQEFRFQPPPLYSEVDPHPGDAQETQPV 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1105	NP_649688.1	Arrestin_N	6..155	CDD:425619	43/154 (28%)
		Arrestin_C	178..310	CDD:214976	38/134 (28%)
Arrdc4	NP_001036057.1	Arrestin_N	19..166	CDD:425619	45/156 (29%)
		Arrestin_C	188..315	CDD:214976	38/134 (28%)
		PPxY motif 1. /evidence=ECO:0000305	347..350		2/13 (15%)
		PPxY motif 2. /evidence=ECO:0000305	392..395		1/2 (50%)