Protein Alignment CG1105 and arrd-19

DIOPT Version :10

• Sequence 1: NP_649688.1
• Gene: CG1105 / 40841
• FlyBaseID: FBgn0037465
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_503917.1
• Gene: arrd-19 / 178764
• WormBaseID: WBGene00018061
• Length: 471
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 133/492 - (27%)
• Similarity: 218/492 - (44%)
• Gaps: 116/492 - (23%)

  Fly    11 DNPWNTYYAGQTVNGQVKFTFDSPK-KVRGIIIRFLGEANTEWSEEKSV--TTSEGKT--ENEVT 70
            :.|...::.|:.::|:|..:....| |.|.:.|:.||.|:|.|::.:.|  ..:|||.  |.::.
 Worm    11 NQPDEVFHPGKPISGRVVLSTTKEKYKARAVNIKILGLAHTSWTDTERVRKVNAEGKETYETKIV 75

  Fly    71 QLKGHEEYFKIQY-YLLGGKNSSETELPPGTHTYPFTCALPPNLPSSFEGEFGHVRYTIKVTLDR 134
            ....:..|  :.| .||...:....||..|.:.:||:..||.|:|.||||::|::||::...:||
 Worm    76 NYSANVNY--LDYSLLLWASSDGSNELAAGEYAWPFSYTLPINVPPSFEGKYGYLRYSVTAEIDR 138

  Fly   135 PWKFDQDMKMAFTVIAPVDLNLNPRVKEPFKLELEKSFCCFCCRSGPLAVITNIPQTGFVSGQVL 199
            ||:.|:|.|...||...:|||:.|........:..::..|.|...|.|.:..|||:||||.|:.:
 Worm   139 PWRVDKDKKRCITVSPLIDLNVIPHALTQINDQASENLGCCCFTKGYLELRVNIPKTGFVPGETV 203

  Fly   200 PITCEVDNTSNVNLTAVKFELRK-----------LVTFH-------TNQPRSEKRESKVII---A 243
            |:...:.|.|:|.:|.||.::.:           .||:.       :...:..:.:::.::   .
 Worm   204 PMNIHILNHSSVPVTKVKAKIIQQCKFIAYRNGTTVTYDGGYETSTSGMLQETQHDTRTVVKQGL 268

  Fly   244 NLSVGPVNGGESRTFTQQMEIPALPPTNLLNCGIIALDY--DLHVE----------CEVSGPHRN 296
            .:.|.|.|   ...|..::.:|::.||......:|.::|  ..|||          ||:|
 Worm   269 EMKVAPRN---EHKFAMELRLPSVTPTINQFSPVITVEYIVQFHVETSTTCGGNVDCEMS----- 325

  Fly   297 LTGKVPITLGTIPLAGVRPPTQFTDAPSAVQSEDPSLAPTQP-----------VSPAS---PPG- 346
                  |.:||:|::...||        |...:||:|.|:||           |:||.   |||
 Worm   326 ------ILIGTVPISKYLPP--------AYYPQDPNLPPSQPTPIGGGVAPAGVAPAGVVPPPGY 376

  Fly   347 -----GDGVGGALGWNVADSTGGGSLYPNIPP-PQFVETQY--------------RAPTIAGRDD 391
                 .||         .|:..|.:.||..|| |..|...|              .||.::..:.
 Worm   377 GFLPMTDG---------TDNGAGDTPYPVGPPYPSDVPAPYPSGDEPKDGTVVVPSAPPLSYEES 432

  Fly   392 ---SEHTQMIGD---GAFAPRYPTFQ---FNNATAPP 419
               :|.|::..|   ..|||:||.|.   ..|.||||
 Worm   433 MYGTEGTELNTDENAQPFAPKYPVFNDLPVYNPTAPP 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1105	NP_649688.1	Arrestin_N	6..155	CDD:425619	48/149 (32%)
		Arrestin_C	178..310	CDD:214976	37/164 (23%)
arrd-19	NP_503917.1	Arrestin_N	6..159	CDD:425619	48/149 (32%)
		Arrestin_C	182..332	CDD:214976	37/163 (23%)
		PHA03247	<338..470	CDD:223021	42/149 (28%)