DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1105 and Arrdc3

DIOPT Version :10

Sequence 1:NP_649688.1 Gene:CG1105 / 40841 FlyBaseID:FBgn0037465 Length:422 Species:Drosophila melanogaster
Sequence 2:NP_001036056.1 Gene:Arrdc3 / 105171 MGIID:2145242 Length:414 Species:Mus musculus


Alignment Length:341 Identity:103/341 - (30%)
Similarity:172/341 - (50%) Gaps:29/341 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 YYAGQTVNGQVKFTFDSPKKVRGIIIRFLGEANTEWSEEKSVTTSEGKTENEVTQLKGHEEYFKI 81
            |.:|.||:|:|........:|:.:.|...|.|...|:|.::..::...|:|...::    |||..
Mouse    24 YSSGDTVSGRVNLEVTGEIRVKSLKIHARGHAKVRWTESRNAGSNTAYTQNYTEEV----EYFNH 84

  Fly    82 QYYLLGGK----NSSE--TELPPGTHTYPFTCALPPN-LPSSFEGEFGHVRYTIKVTLDRPWKFD 139
            :..|:|.:    ||.|  ..:..|.|.|.|:..||.. |.:||||..|.|||.:|..|.|||...
Mouse    85 KDILIGHERDDDNSEEGFHTIHSGRHEYAFSFELPQTPLATSFEGRHGSVRYWVKAELHRPWLLP 149

  Fly   140 QDMKMAFTVIAPVDLNLNPRVKEPFKLELEKSFCCFCCRSGPLAVITNIPQTGFVSGQVLPITCE 204
            ..:|..|||...:|:| .|.:..|.....||:.||:.|.|||:::...|.:.|:..|:.:.|..|
Mouse   150 VKLKKEFTVFEHIDIN-TPSLLSPQAGTKEKTLCCWFCTSGPISLSAKIERKGYTPGESIQIFAE 213

  Fly   205 VDNTSNVNLTAVKFELRKLVTFHTNQPRSEKRESKVIIANLSVGPVNGGESRTFT-QQMEIPALP 268
            ::|.|: .:...|..:.:...|:.   :.:.:|.|.::|||....::.|::.|:. :.::||.:.
Mouse   214 IENCSS-RMVVPKAAIYQTQAFYA---KGKMKEVKQLVANLRGESLSSGKTETWNGKLLKIPPVS 274

  Fly   269 PTNLLNCGIIALDYDLHVECEVSGPHRNLTGKVPITLGTIPLAGVRPPTQFTDAPSAVQSEDPS- 332
            | ::|:|.||.::|.|.|..::.|. .:|...:|:.:|||||   .|   |....|:|.|:... 
Mouse   275 P-SILDCSIIRVEYSLMVYVDIPGA-MDLLLSLPLVIGTIPL---HP---FGSRTSSVSSQCSMS 331

  Fly   333 ---LAPTQPVSPASPP 345
               ||...|..|.:||
Mouse   332 MNWLALALPERPEAPP 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1105NP_649688.1 Arrestin_N 6..155 CDD:425619 47/144 (33%)
Arrestin_C 178..310 CDD:214976 35/132 (27%)
Arrdc3NP_001036056.1 Arrestin_N 22..165 CDD:425619 47/144 (33%)
Arrestin_C 187..314 CDD:214976 35/132 (27%)
PPxY motif 1. /evidence=ECO:0000305 346..349 2/2 (100%)
PPxY motif 2. /evidence=ECO:0000305 391..394
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 393..414
Blue background indicates that the domain is not in the aligned region.

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