DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sodh-1 and SOR2

DIOPT Version :9

Sequence 1:	NP_001287203.1	Gene:	Sodh-1 / 40836	FlyBaseID:	FBgn0024289	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_010035.1	Gene:	SOR2 / 851351	SGDID:	S000002405	Length:	357	Species:	Saccharomyces cerevisiae

Alignment Length:	348	Identity:	163/348 - (46%)
Similarity:	220/348 - (63%)	Gaps:	5/348 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NLTAVLHGIEDMRLEQRPIPEIADDE-VLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIGHES 68
            |...||..:.|:.:||||||.|.|.. |.||:.:.||||||:||...|.||.::|..||::||||
Yeast     6 NPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMVLGHES 70

  Fly    69 AGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPPYDGNLTRYYKHAA 133
            :|.|.::|..||.:|||||||||||||.|..|..|:|.|||||.|.|.||||.||.|.:||....
Yeast    71 SGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPE 135

  Fly   134 DFCFKLPDHVTMEEGALLEPLSVGVHACKRAEVTLGSKVLILGAGPIGLVTLMAAQAMGASEILI 198
            ||..|||:.|:.||||.:||||||||:.|.|.|..|:||::.||||:||:|...|:|.||::::.
Yeast   136 DFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIF 200

  Fly   199 TDLVQQRLDVAKELGATHTLLLKRDQT--AEETAVLVQKTMGG-QPDKSIDCCGAESSARLAIFA 260
            .|:...:|..||:.|||:|....:..|  |::.|..|||.:|| ..|...:|.||:.....|:..
Yeast   201 VDVFDNKLQRAKDFGATNTFNSSQFSTDKAQDLADGVQKLLGGNHADVVFECSGADVCIDAAVKT 265

  Fly   261 TRSGGIVVVVGMGAAEIKLPLINALAREVDIRGVFRYC-NDYAAALALVASGKVNVKRLVTHHFD 324
            |:.||.:|.||||......|:.....:|:.:.|.|||. .||..|:.|||:||||||.|:||.|.
Yeast   266 TKVGGTMVQVGMGKNYTNFPIAEVSGKEMKLIGCFRYSFGDYRDAVNLVATGKVNVKPLITHKFK 330

  Fly   325 IKETAKAFETSRKGLGGAIKVMI 347
            .::.|||::.:....|..:|.:|
Yeast   331 FEDAAKAYDYNIAHGGEVVKTII 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sodh-1	NP_001287203.1	PLN02702	4..346	CDD:215378	162/345 (47%)
Sodh-1	NP_001287203.1	sorbitol_DH	8..349	CDD:176188	162/345 (47%)
SOR2	NP_010035.1	sorbitol_DH	8..353	CDD:176188	161/344 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	143	1.000	Domainoid score	I996
eggNOG	1	0.900	-	-		E1_COG1063
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56080
Inparanoid	1	1.050	305	1.000	Inparanoid score	I487
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56613
OrthoFinder	1	1.000	-	-		FOG0001480
OrthoInspector	1	1.000	-	-		mtm9250
orthoMCL	1	0.900	-	-		OOG6_100349
Panther	1	1.100	-	-	O	PTHR43161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X751
TreeFam	1	0.960	-	-
	13	12.830