Protein Alignment Antp and ISX

DIOPT Version :10

• Sequence 1: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001290437.1
• Gene: ISX / 91464
• HGNCID: 28084
• Length: 245
• Species: Homo sapiens
• Alignment Length: 130
• Identity: 44/130 - (33%)
• Similarity: 66/130 - (50%)
• Gaps: 15/130 - (11%)

  Fly   248 MHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLYPWMRSQFGKCQERKRGRQTYTRYQTLEL 312
            |.:.:||.:  :| ||:..       :..||:..|  |..:.|.|: :.::|.|.|:|..|..||
Human    46 MDRPEGPGE--EG-PGEAA-------ASGSGLEKP--PKDQPQEGR-KSKRRVRTTFTTEQLHEL 97

  Fly   313 EKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENK--TKGEPGSGGEGDEITPPN 375
            ||.|||..|.....|.::|..:.|.|.:::|||||:|.||:|:.|  ..|.|....|.....|.|
Human    98 EKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTN 162

  Fly   376  375
            Human   163  162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	15/57 (26%)
		Homeodomain	298..354	CDD:459649	25/55 (45%)
ISX	NP_001290437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..86		13/52 (25%)
		Homeodomain	83..139	CDD:459649	25/55 (45%)